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A package insert from 1970, with Ovrette brand contraception pills. A package insert is a document included in the package of a medication that provides information about that drug and its use. For prescription medications, the insert is technical, providing information for medical professionals about how to prescribe the drug.
Ulipristal acetate, sold under the brand name Ella among others, is a medication used for emergency contraception (birth control) and uterine fibroids. [1] [7] [8] As emergency contraception it should be used within 120 hours of vaginally penetrating intercourse. [1] For fibroids it may be taken for up to six months. [9] It is taken by mouth. [1]
However, people with medical conditions may need to have contraceptive options tailored around their specific needs. [1] Resources exist for patients and providers to help tailor methods. One example of a resource is the Medical Eligibility Criteria for Contraceptive Use (MEC), [2] [3] which exists in multiple formats.
Examples of contraindications to estrogen-containing methods of contraception include relatively common conditions such as hypertension, migraine headaches with aura, or a history of pulmonary embolism or deep vein thrombosis. [37] On the other hand, progestogen-only pills are safe for use by all these groups. [38]
Contraindications include an allergy to the medication, pregnancy, prior liver problems, abnormal vaginal bleeding of unclear cause, ovarian cysts other than those due to polycystic ovarian syndrome, unmanaged adrenal or thyroid problems, and pituitary tumors.
Modern contraceptives using steroid hormones have perfect-use or method failure rates of less than 1% per year. The lowest failure rates are seen with the implants Jadelle and Implanon, at 0.05% per year. [9] [10] According to Contraceptive Technology, none of these methods has a failure rate greater than 0.3% per year. [10]
NETE is a prodrug of norethisterone in the body. [13] Upon reaching circulation, it is rapidly converted into norethisterone by esterases.Hence, as a prodrug of norethisterone, NETE has essentially the same effects as norethisterone, acting as a potent progestogen with additional weak androgenic and estrogenic activity (the latter via its metabolite ethinylestradiol). [14]
A contraceptive implant is an implantable medical device used for the purpose of birth control. The implant may depend on the timed release of hormones to hinder ovulation or sperm development, the ability of copper to act as a natural spermicide within the uterus , or it may work using a non-hormonal, physical blocking mechanism.