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Overuse of antimicrobial agents and problems with infection control practices have led to the development of multidrug-resistant gram-negative bacterial infections. We used to use carbapenems as the main option in several countries for those severe infections; however, now there are several mechanisms of resistance, including carbapenemase ...
Infection prevention is the most efficient strategy of prevention of an infection with a MDR organism within a hospital, because there are few alternatives to antibiotics in the case of an extensively resistant or panresistant infection; if an infection is localized, removal or excision can be attempted (with MDR-TB the lung for example), but ...
One major drawback to phage therapy is the evolution of phage-resistant microbes which was seen in a majority of phage therapy experiments aimed to treat sepsis and intestinal infection. [10] Recent studies suggest that development of phage resistance comes as a trade-off for antibiotic resistance and can be used to create antibiotic-sensitive ...
Multidrug-resistant tuberculosis (MDR-TB) is a form of tuberculosis (TB) infection caused by bacteria that are resistant to treatment with at least two of the most powerful first-line anti-TB medications (drugs): isoniazid and rifampicin.
ESKAPE is an acronym comprising the scientific names of six highly virulent and antibiotic resistant bacterial pathogens including: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. [1] The acronym is sometimes extended to ESKAPEE to include Escherichia coli. [2]
Once a person is infected, Marburg can spread through human-to-human transmission via direct contact with blood, secretions, organs or other bodily fluids of these individuals and with surfaces ...
A fatal virus has been discovered in shrews in Alabama, sparking concerns about potential contagion to humans. The Camp Hill virus was discovered by researchers at The University of Queensland.
In other cases, the virus can cause systemic disease through a disseminated infection spread throughout the body. The predominant mode of viral dissemination occurs through the blood or lymphatic system , some of which include viruses responsible for chickenpox ( varicella zoster virus ), smallpox ( variola ), HIV ( human immunodeficiency virus ).