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Thyroid follicular cells form a simple cuboidal epithelium and are arranged in spherical thyroid follicles surrounding a fluid filled space known as the colloid. The interior space formed by the follicular cells is known as the follicular lumen .
Follicular cells vary in shape from flat to cuboid to columnar, depending on how active they are. [4] [15] Follicular lumen. The follicular lumen is the fluid-filled space within a follicle of the thyroid gland. There are hundreds of follicles within the thyroid gland. A follicle is formed by a spherical arrangement of follicular cells.
PP cell (F cell, gamma cell) Delta cell; Epsilon cell; Pharyngeal pouch. Thyroid gland Follicular cell; Parafollicular cell [3] Parathyroid gland. Parathyroid chief cell;
Parafollicular cells, also called C cells, are neuroendocrine cells in the thyroid. They are called C cells because the primary function of these cells is to secrete calcitonin. [1] They are located adjacent to the thyroid follicles and reside in the connective tissue. These cells are large and have a pale stain compared with the follicular cells.
The thyroid hormones cross the follicular cell membrane towards the blood vessels by an unknown mechanism. [31] Text books have stated that diffusion is the main means of transport, [45] but recent studies indicate that monocarboxylate transporter (MCT) 8 and 10 play major roles in the efflux of the thyroid hormones from the thyroid cells. [32 ...
Thyroglobulin (Tg) is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Tg is secreted and accumulated at hundreds of grams per litre in the extracellular compartment of the thyroid follicles, accounting for approximately half of the protein content of the thyroid gland. [5]
Hormonal changes and medical conditions: "Medical conditions like thyroid disorders, polycystic ovary syndrome (PCOS), and autoimmune diseases can influence hair growth," Dr. Kinler says ...
Thyroid hormone synthesis, with Pendrin seen at center between the follicular colloid and the follicular cell. In the thyroid, pendrin is expressed by thyroid follicular cells. Na + /I − symporter imports iodide (I −) into the cell across its basolateral side, and pendrin extrudes the I − across the cell's apical membrane into the thyroid ...