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2. Host–pathogen interaction - Wikipedia

   en.wikipedia.org/wiki/Host–pathogen_interaction

   Viruses, however, use a completely different mechanism to cause disease. Upon entry into the host, they can do one of two things. Many times, viral pathogens enter the lytic cycle; this is when the virus inserts its DNA or RNA into the host cell, replicates, and eventually causes the cell to lyse, releasing more viruses into the environment.

3. Viral pathogenesis - Wikipedia

   en.wikipedia.org/wiki/Viral_pathogenesis

   Virus factors encoded in the genome often control the tropism, routes of virus entry, shedding and transmission. In polioviruses, the attenuating point mutations are thought to induce a replication and translation defect to reduce the virus' ability of cross-linking to host cells and replicate within the nervous system.

4. Virulence factor - Wikipedia

   en.wikipedia.org/wiki/Virulence_factor

   immunoevasion, evasion of the host's immune response [1] [2] [3] immunosuppression, inhibition of the host's immune response (this includes leukocidin-mediated cell death) [1] entry into and exit out of cells (if the pathogen is an intracellular one) [4] obtain nutrition from the host [1] Specific pathogens possess a wide array of virulence ...

5. Viral strategies for immune response evasion - Wikipedia

   en.wikipedia.org/wiki/Viral_strategies_for...

   At the same time, viruses have co-evolved evasion machinery to address the many ways that host organisms attempt to eradicate them. DNA and RNA viruses use complex methods to evade immune cell detection through disruption of the Interferon Signaling Pathway, remodeling of cellular architecture, targeted gene silencing, and recognition protein ...

6. Infection - Wikipedia

   en.wikipedia.org/wiki/Infection

   The appearance and severity of disease resulting from any pathogen depend upon the ability of that pathogen to damage the host as well as the ability of the host to resist the pathogen. However, a host's immune system can also cause damage to the host itself in an attempt to control the infection.

7. Virulence - Wikipedia

   en.wikipedia.org/wiki/Virulence

   Many viruses can exist inside a host for long periods during which little damage is done. Extremely virulent strains can eventually evolve by mutation and natural selection within the virus population inside a host. The term "neurovirulent" is used for viruses such as rabies and herpes simplex which can invade the nervous system and cause ...