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Animal testing, also known as animal experimentation, animal research, and in vivo testing, is the use of non-human animals, such as model organisms, in experiments that seek to control the variables that affect the behavior or biological system under study. This approach can be contrasted with field studies in which animals are observed in ...
The Johns Hopkins University Center for Alternatives to Animal Testing (CAAT) has worked with scientists, since 1981, to find new methods to replace the use of laboratory animals in experiments, reduce the number of animals tested, and refine necessary tests to eliminate pain and distress (the Three Rs as described in Russell and Burch's Principles of Humane Experimental Technique). [1]
An animal model (short for animal disease model) is a living, non-human, often genetic-engineered animal used during the research and investigation of human disease, for the purpose of better understanding the disease process without the risk of harming a human. Although biological activity in an animal model does not ensure an effect in humans ...
Plant development is the process by which structures originate and mature as a plant grows. It is studied in plant anatomy and plant physiology as well as plant morphology. Plants constantly produce new tissues and structures throughout their life from meristems [ 36 ] located at the tips of organs, or between mature tissues.
The directive stresses the use of the 3R principle (replacement, refinement, reduction) and animal welfare when conducting animal testing on non-human primates. [21] A 2013 amendment to the German Animal Welfare Act, with special regulations for monkeys, resulted in a near total ban on the use of great apes as laboratory animals. [22]
Specific-pathogen-free (SPF) is a term used for laboratory animals that are guaranteed free of particular pathogens. Use of SPF animals ensures that specified diseases do not interfere with an experiment. For example, absence of respiratory pathogens such as influenza is desirable when investigating a drug's effect on lung function.
In 1954, the Universities Federation for Animal Welfare (UFAW) decided to sponsor systematic research on the progress of humane techniques in the laboratory. [2] In October of that year, William Russell, described as a brilliant young zoologist who happened to be also a psychologist and a classical scholar, and Rex Burch, a microbiologist, were appointed to inaugurate a systematic study of ...
The human population exploits and depends on many animal and plant species for food, mainly through agriculture, but also by exploiting wild populations, notably of marine fish. [ 10 ] [ 11 ] [ 12 ] Livestock animals are raised for meat across the world; they include (2011) around 1.4 billion cattle , 1.2 billion sheep and 1 billion domestic pigs .