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Margin positivity is strongly correlated with PSA recurrences and a fourfold annual increase in cancer recurrence compared to men with negative surgical margins. There was a recent study from the University of Michigan by Hollenbeck et al. (Urology 2007; 70: 96-100) after their first 200 cases that they were able to eliminate extensive positive ...
Cryosurgery is a minimally invasive method of treating prostate cancer in which the prostate gland is exposed to freezing temperatures. [14] Under ultrasound guidance metal rods are inserted through the skin of the perineum into the prostate. Highly purified argon gas is used to cool the rods, freezing the surrounding tissue at −186 °C (− ...
In prostate cancer, the abnormal cells spread beyond the boundaries of the acinus and form clusters without basal cells. In HGPIN, the basal cell layer is disrupted but present. PIN is primarily found in the peripheral zone of the prostate (75-80%), rarely in the transition zone (10-15%) and very rarely in the central zone (5%), a distribution ...
Less often, orchiectomy is used to treat prostate cancer. Prostate cancer grows in the presence of testosterone. When testosterone is present, " it is metabolized and converted into dihydrotestosterone (DHT) which stimulates the growth of prostate cells. This leads to normal prostate growth in adolescents but contributes to abnormal cell growth ...
Prostatectomy (from the Greek προστάτης prostátēs, "prostate" and ἐκτομή ektomē, "excision") is the surgical removal of all or part of the prostate gland. This operation is done for benign conditions that cause urinary retention, as well as for prostate cancer and for other cancers of the pelvis.
The glands may be the source of female ejaculation, [3] [4] [5] but this has not been proven. [4] Because they and the male prostate act similarly by secreting prostate-specific antigen (PSA), which is an ejaculate protein produced in males, and prostatic acid phosphatase, some authors refer to the Skene's glands as the "female prostate".
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