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The mammillary bodies also mamillary bodies, are a pair of small round brainstem nuclei. [2] They are located on the undersurface of the brain that, as part of the diencephalon, form part of the limbic system. They are located at the ends of the anterior arches of the fornix. [3]
The mammillary bodies are two clusters of cell bodies found at the ends of the posterior fibres of the fornix within the diencephalon. The mammillary bodies relay information from the hippocampal formation (via the fornix) to the thalamus (via the mammillothalamic tract). The mammillary bodies are integral parts of the limbic system and have ...
The mammillary bodies are an important part of the Papez circuit. If there is damage, such as loss of neurons and/or myelination, to the mammillary bodies, the Papez circuit can be severely affected. There will be a disruption in the connecting parts of the system.
In the 1960s, Dr. MacLean enlarged his theory to address the human brain's overall structure and divided its evolution into three parts, an idea that he termed the triune brain. In addition to identifying the limbic system, he hypothesized a supposedly more primitive brain called the R-complex, related to reptiles, which controls basic ...
Brain at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (view tree for regions of the brain) BrainMaps.org; BrainInfo (University of Washington) "Brain Anatomy and How the Brain Works". Johns Hopkins Medicine. 14 July 2021. "Brain Map". Queensland Health. 12 July 2022.
The posterior fibers (called the postcommissural fornix) of each side continue through the hypothalamus to the mammillary bodies; then to the anterior nuclei of thalamus via the mammillothalamic tract. The anterior fibers (precommissural fornix) end at the septal nuclei of the basal forebrain and nucleus accumbens of each half of the brain.
The mammillary bodies directly or indirectly connect to the amygdala, hippocampus, and thalami as major structures in the limbic system. [6] The mammillothalamic tract carries signals from the mammillary bodies via the anterior thalamus to support spatial memory .
The tuber cinereum is a convex mass of grey matter, [3]: 495 a ventral/inferior distention of the hypothalamus forming the floor of the third ventricle. [citation needed] The portion of the tuber cinerum at the base of the infundibulum (pituitary stalk) is the median eminence; [2] the infundibulum extends ventrally/inferiorly from the median eminence to become continuous with the infundibulum.