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Cervical intraepithelial neoplasia (CIN), also known as cervical dysplasia, is the abnormal growth of cells on the surface of the cervix that could potentially lead to cervical cancer. [1] More specifically, CIN refers to the potentially precancerous transformation of cells of the cervix.
LEEP cone biopsy displaying normal cervical epithelium (far left) progressing to borderline koilocytosis, to LSIL, and to HSIL (far right). A squamous intraepithelial lesion (SIL) is an abnormal growth of epithelial cells on the surface of the cervix, commonly called squamous cells.
ThinPrep pap smear with group of normal cervical cells on left and HPV-infected cells showing features typical of koilocytes: enlarged (x2 or x3) nuclei and hyperchromasia. A koilocyte is a squamous epithelial cell that has undergone a number of structural changes, which occur as a result of infection of the cell by human papillomavirus (HPV). [1]
The cells on the 'outside' of the cervix are typically squamous epithelial cells. Where the two cells meet is called the transformation zone, also known as the stratified squamous epithelium . Cervical ectropion can be grossly indistinguishable from early cervical cancer and must be evaluated by a physician to determine risks and prognosis.
Cervical cancer is a cancer arising from the cervix or in any layer of the wall of the cervix. [2] It is due to the abnormal growth of cells that can invade or spread to other parts of the body. [12] Early on, typically no symptoms are seen. [2] Later symptoms may include abnormal vaginal bleeding, pelvic pain or pain during sexual intercourse. [2]
Cervical cancer is screened either through an human papillomavirus (HPV) test, which looks for high-risk HPV, or Pap test, which looks for abnormal cells, both conducted the same way—by a ...
The doctors eventually discovered abnormal cells that had to be removed along with "a lot" of her cervix, which felt like "my entire uterus had fallen onto the bathroom floor," she said.
Cervical cancer screening, such as the Papanicolaou test ("pap smear"), or examination of the cervix after applying acetic acid, can detect both early cancer and abnormal cells that may develop into cancer. [1] Screening allows for early treatment which results in better outcomes. [1]