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This is the phenomenon of various primary tumors developing in one particular area of the body, suggesting that an earlier "hit" predisposed the whole area for cancer. [citation needed] Announced in 2011, chromothripsis similarly involves multiple mutations, but asserts that they may all appear at once.
Second-impact syndrome (SIS) occurs when the brain swells rapidly, and catastrophically, after a person has a second concussion before symptoms from an earlier one have subsided. This second blow may occur minutes, days, or weeks after an initial concussion, [ 1 ] and even the mildest grade of concussion can lead to second impact syndrome. [ 2 ]
Oxidative stress, hormonal imbalances, and mitochondrial abnormalities are potential causes of this "second hit" phenomenon. [27] A further nutrigenomics model named multiple hit extends the second hit model, suggesting that multiple disease biomarkers and factors such as genes and nutrition influence NAFLD and NASH progression.
Jon Berti's second hit of the game was a go-ahead RBI single in the eighth inning, helping the Miami Marlins to a 6-5 win over the Detroit Tigers on Friday night. Luis Arraez doubled and had two ...
Second wind is a phenomenon in endurance sports, such as marathons or road running (as well as other sports), whereby an athlete who is out of breath and too tired to continue (known as "hitting the wall"), finds the strength to press on at top performance with less exertion.
Clemens, the cookbook author, recently published his second book of Sriracha recipes, this time focusing on vegan and gluten-free dishes. Perhaps Sriracha's greatest virtue is its mind-blowing ...
A Long Island driver lost control and slammed into a Chinese restaurant in a fiery crash Monday night – the second time a motorist struck the eatery in about a year, cops said. A 57-year-old ...
Second Hit: While the second hit is commonly assumed to be a deletion that results in loss of the remaining functioning TSG allele, the original published mechanism of RB1 LOH was mitotic recombination/gene conversion/copy-neutral LOH, not deletion. There is a critical difference between deletion and CN-LOH, as the latter mechanism cannot be ...