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Hillsville is located in central Carroll County at (36.758814, −80.734510 U.S. Routes 52, 221 and 58 intersect in the center of town. US 52 leads northwest 28 miles (45 km) to Wytheville and south 22 miles (35 km) to Mount Airy, North Carolina, while US 221 leads northeast 70 miles (110 km) to Roanoke and southwest 13 miles (21 km) to Galax.
In Virginia, the U.S. Highway runs 149.61 miles (240.77 km) from the North Carolina state line near Independence north to its northern terminus at US 29 Business, US 460 Business, and US 501 Business in Lynchburg. US 221 connects Independence, Galax, and Hillsville in Southwest Virginia while running concurrently with US 58.
US 221 travels concurrently with its parent to Independence, Virginia. Virginia US 21 / US 58 in Independence. US 58/US 221 travels concurrently to Hillsville. Future I-74 / I-77 in Woodlawn US 52 in Hillsville US 11 in Roanoke. The highways travel concurrently through Roanoke. Future I-73 / I-581 / US 220 in Roanoke US 11 / US 460 in Roanoke.
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Interstate 77 (I-77) in the US state of Virginia is a 67-mile (108 km) north–south Interstate Highway serving Hillsville, Wytheville, and Bland.Running parallel to US Route 52 (US 52), I-77 passes through the Big Walker Mountain Tunnel and East River Mountain Tunnel, the latter on the West Virginia state line and one of only two land vehicular tunnels to cross a state line.
It enters Virginia from North Carolina in the town of Cana, Virginia as a two-lane road known as Fancy Gap Highway. In the town of Fancy Gap there is an interchange with the Blue Ridge Parkway , and at the center of town an intersection with SR 755 (Chances Creek Road) provides access to I-77.
U.S. Route 58 (US 58) is an east–west U.S. Highway that runs for 508 miles (818 km) from U.S. Route 25E just northwest of Harrogate, Tennessee, to U.S. Route 60 in Virginia Beach, Virginia. Until 1996, when the Cumberland Gap Tunnel opened, US 58 ran only inside the commonwealth of Virginia (and it now runs only about 1 mile outside of ...
The state highway runs 53.31 miles (85.79 km) from U.S. Route 221 (US 221) in Hillsville north to SR 61 in Narrows. SR 100 is one of the major highways of the New River Valley , connecting Narrows and Pearisburg in Giles County with Dublin , Pulaski (via US 11 ), and Interstate 81 (I-81) in Pulaski County .