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Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). [ 2 ] [ 3 ] [ 4 ] Salts of this anion, especially docusate sodium , are widely used in medicine as an emollient laxative and as stool softeners , by mouth or rectally. [ 1 ]
Dosage Fforms Strengths Brand names Manufacturer Oral: Capsules, extended-release: 150 mg (50 mg iron) with Docusate Sodium 100 mg* Ferrous Fumarate with DSS® Timed Capsules: Vita-Rx Tablets, extended-release, film-coated: 150 mg (50 mg iron) with Docusate Sodium 100 mg: Ferro-DSS® Caplets® Time-Caps Ferro-Sequels® Inverness
Calcium dobesilate is a vasoprotective.It is the calcium salt of dobesilic acid.It is a synthetic molecule with the ability to reduce capillary permeability in the body. In Switzerland the drug is sold by the pharmaceutical company OM Pharma under the trade name of Doxium in capsules containing 500 mg of active ingredient.
Laxatives vary as to how they work and the side effects they may have. Certain stimulant, lubricant, and saline laxatives are used to evacuate the colon for rectal and bowel examinations, and may be supplemented by enemas under certain circumstances. Sufficiently high doses of laxatives may cause diarrhea.
A 2018 pooled analysis from three phase III, randomized, double-blind, placebo-controlled studies on usage for Opioid-Induced Constipation, found that the numbers of patients reporting adverse effects were similar in both the lubiprostone and placebo treatment groups for all opioid classes (P ≥ 0.125); however, gastrointestinal adverse ...
Common side effects of senna glycoside include abdominal cramps. [3] It is not recommended for long-term use, as it may result in poor bowel function or electrolyte problems. [1] While no harm has been found to result from use while breastfeeding, such use is not typically recommended. [1] It is not typically recommended in children. [1]
ATC code A06 Drugs for constipation is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Side effects of doxylamine include dizziness, drowsiness, and dry mouth, among others. [4] Doxylamine is a potent anticholinergic and has a side-effect profile common to such drugs, including blurred vision , dry mouth, constipation , muscle incoordination , urinary retention , mental confusion , and delirium .