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Most children with progeria appear normal at birth and during early infancy. [11] Children with progeria usually develop the first symptoms during their first few months of life. The earliest symptoms may include a failure to thrive and a localized scleroderma-like skin condition. As a child ages past infancy, additional conditions become ...
Common symptoms present in the different types of leprosy include a runny nose; dry scalp; eye problems; skin lesions; muscle weakness; reddish skin; smooth, shiny, diffuse thickening of facial skin, ear, and hand; loss of sensation in fingers and toes; thickening of peripheral nerves; a flat nose from the destruction of nasal cartilages; and changes in phonation and other aspects of speech ...
Tzaraath (Hebrew: צָרַעַת ṣāraʿaṯ), variously transcribed into English and frequently translated as leprosy (though it is not Hansen's disease, the disease known as "leprosy" in modern times [1]), is a term used in the Bible to describe various ritually impure disfigurative conditions of the human skin, [2] clothing, [3] and houses. [4]
It is the most widely used vaccine worldwide, with more than 90% of all children being vaccinated. [14] The immunity it induces decreases after about ten years. [ 14 ] As tuberculosis is uncommon in most of Canada, Western Europe, and the United States, BCG is administered to only those people at high risk.
A representation by Robert Seymour of the cholera epidemic depicts the spread of the disease in the form of poisonous air.. The miasma theory was the predominant theory of disease transmission before the germ theory took hold towards the end of the 19th century; it is no longer accepted as a correct explanation for disease by the scientific community.
The euphemism of "a long illness" to describe cancers leading to death is still commonly used in obituaries, rather than naming the disease explicitly, reflecting an apparent stigma. [229] Cancer is also euphemised as "the C-word"; [ 230 ] [ 231 ] [ 232 ] Macmillan Cancer Support uses the term to try to lessen the fear around the disease. [ 233 ]
SMBA is the first "CAG / polygutamine" disease, which is a subcategory of repeat disorders. [9] In 1992, for myotonic dystrophy type 1 (DM1), CTG expansion was found in the myotonic dystrophy protein kinase (DMPK) 3' UTR. In 1993, for Huntington's disease (HD), a longer-than-usual CAG repeat with was found in the exon 1 coding sequence. [10]
Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.