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However, these cells did not self-renew and were subsequently depleted as they generated new neurons, thus failing to satisfy the requirement for stem cells. [6] [7] One study observed that ependymal cells from the lining of the lateral ventricle might be a source for cells which can be transplanted into the cochlea to reverse hearing loss. [8]
This schematic illustrates the four different types of glial cells, all of which possess cytoplasmic processes: ependymal cells (light pink), astrocytes (green), microglia (red), and oligodendrocytes (light blue). Cell bodies of neurons are in yellow (Their axons are surrounded by myelin, produced by oligodendrocytes).
Ependymomas are composed of cells with regular, round to oval nuclei. There is a variably dense fibrillary background. Tumor cells may form gland-like round or elongated structures that resemble the embryologic ependymal canal, with long, delicate processes extending into the lumen; more frequently present are perivascular pseudorosettes in which tumor cells are arranged around vessels with an ...
Ependymal cells secrete high molecular mass glycoproteins into the cerebrospinal fluid, in which the bulk of them condense to form a filamentous structure named Reissner's fiber. [4] The subcommissural organ/ Reissner's fiber complex is thought to be involved in the reabsorption and circulation of the cerebrospinal fluid, and with functions ...
The tela choroidea (or tela chorioidea) is a region of meningeal pia mater that adheres to the underlying ependyma, and gives rise to the choroid plexus in each of the brain’s four ventricles.
The central canal (also known as spinal foramen or ependymal canal) is the cerebrospinal fluid-filled space that runs through the spinal cord. [1] The central canal lies below and is connected to the ventricular system of the brain , from which it receives cerebrospinal fluid, and shares the same ependymal lining.
Related to its secretory function, the SCO is partially composed of ependymal cells. [1] [30] These ependymocytes are characterized by elongated cell bodies that contain secretory materials and are covered in cilia. [1] [30] The most prominent of these is the glycoprotein SCO-spondin. [31]
The spinal cord ependymal cells also reside in the FP region of the spinal cord. These cells are a neural stem cell population responsible for repopulating lost cells during injury. These cells have the capacity to differentiate into progenitor glial populations. During injury, a factor entitled Akhirin is secreted in the FP region.