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A549 cells are adenocarcinomic human alveolar basal epithelial cells, and constitute a cell line that was first developed in 1972 by D. J. Giard, et al. through the removal and culturing of cancerous lung tissue in the explanted tumor of a 58-year-old caucasian male. [1]
A549 cells – derived from a cancer patient lung tumor; HeLa cells – a widely used human cell line isolated from cervical cancer patient Henrietta Lacks; HEK 293 cells – derived from human fetal cells; Huh7 cells – hepatocyte-derived carcinoma cell line; Jurkat cells – a human T lymphocyte cell line isolated from a case of leukemia
A549 may refer to: A549 (cell line), a carcinomic human alveolar basal epithelial cell; A549 road (Wales), a road in Great Britain This page was last edited on 27 ...
NCI/ADR-RES appears to have been derived at some point in time from cell line OVCAR-8. [8] Originally the cell line was named MCF-7/ADR-RES; it was renamed together with the change in classification. [8] Two brain cancer cell lines, SNB-19 and U251, were discovered to come from the same person. [9] This makes a mixup likely.
The story of how the HeLa cell line came to be was also the subject of a 2010 episode of the podcast Radiolab. [69] HeLa cells were the subject of a 2010 book by Rebecca Skloot, The Immortal Life of Henrietta Lacks, investigating the historical context of the cell line and how the Lacks family was involved in its use. [14]
A549 cells share the same characteristics with the alveolar type II cells. ... "The human alveolar epithelial cell line A549 may be anchored or suspended in a ...
[38] [7] Putative inhibitors of CYP2J2 inhibit the growth in culture of several human cancer cell lines that express relatively high levels of CYP2J2 viz., Tca-8113 cells, HeLa uterine cervix cell lines, A549 cells, MDA-MB-435 breast cells, and HepG2 cells but they had no significant inhibitory effects on two cell lines that expressed little or ...
This activation may contribute to the ability of 15(S)-HETE to inhibit the growth of cultured human prostate cancer PC-3, LNCaP, and DU145 cell lines and non-malignant human prostate cells; [61] [62] lung adenocarcinoma A549 cells; [63] human colorectal cancer cells; [64] corneal epithelial cells; [65] and Jurkat T-cell leukemia cells. [66]
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