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However, icaridin was also non-toxic in a 21-day reproduction test on the water flea Daphnia magna [22] and a 32-day early life-stage test in zebrafish. [23] Since only the icaridin content of the tested repellent product is known, the observed effects cannot be readily attributed to icaridin.
These safety phrases were used internationally and not just in Europe, and there is an ongoing effort towards complete international harmonization. This harmonization would be carried out by the United Nations 's Globally Harmonized System of Classification and Labelling of Chemicals , that replaced Directive 67/548/EEC under CLP Regulation .
Precautionary statements form part of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS). [1] They are intended to form a set of standardized phrases giving advice about the correct handling of chemical substances and mixtures, which can be translated into different languages.
Icariin is a chemical compound classified as a prenylated flavonol glycoside, a type of flavonoid.It is the 8-prenyl derivative of kaempferol 3,7-O-diglucoside.The compound has been isolated from several species of plant belonging to the genus Epimedium which are commonly known as horny goat weed, Yin Yang Huo, [1] and Herba epimedii. [2]
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The soap is produced at the Fábrica de Jabón La Corona in Ecatepec, Mexico State. [1] Most of the brand's sales are domestic, with 15% of sales outside of Mexico, primarily in the United States and South America. [5] According to the company, soap sales increased by 20% in 2020 amid the covid pandemic. [1]
Ethyl butylacetylaminopropionate is an insect repellent whose trade name is IR3535 and was developed and commercialized by Merck KGaA (Germany). It is a colorless and odorless oil with a good skin feel in final products, and it is biodegradable.
Using soap helps dissolve many water-insoluble substances, like fats and oils, making them washable with water. In most cases, hard soaps or products based on them are used for handwashing because they exhibit an alkaline ( pH value above 7) nature and can irritate the skin when in contact with mucous membranes.