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Insulin detemir was approved for medical use in the European Union in June 2004, and in the United States in June 2005. [5] [6] [8] It is on the World Health Organization's List of Essential Medicines. [9] In 2022, it was the 127th most commonly prescribed medication in the United States, with more than 4 million prescriptions. [10] [11]
- Intermediate acting (i.e NPH insulin) with onset in 2 hours and duration of about 14 hrs. - Long acting (i.e. detemir) with onset in 1 hr. and duration of about 24 hrs. - Premixed which are usually combinations of short and long acting insulin. Insulin is usually taken several times per day in patients who require it to control their diabetes ...
In 2004 continuous glucose monitoring (CGM) was introduced. A small sensor placed under the skin for three days (by 2013 up to 14 days) would measure glucose continuously and transmit the results to a receiver, which would periodically be connected to a PC to produce reports for the health care provider.
Glucose testing can be used to diagnose or indicate certain medical conditions. [citation needed]High blood sugar may indicate . gestational diabetes.This temporary form of diabetes appears during pregnancy, and with glucose-controlling medication or insulin symptoms can be improved.
Blood glucose monitoring is the use of a glucose meter for testing the concentration of glucose in the blood ().Particularly important in diabetes management, a blood glucose test is typically performed by piercing the skin (typically, via fingerstick) to draw blood, then applying the blood to a chemically active disposable 'test-strip'.
An insulin tolerance test (ITT) is a medical diagnostic procedure during which insulin is injected into a patient's vein, after which blood glucose is measured at regular intervals. This procedure is performed to assess pituitary function, adrenal function, insulin sensitivity , [ 1 ] [ 2 ] and sometimes for other purposes.
The glucose tolerance test was first described in 1923 by Jerome W. Conn. [4]The test was based on the previous work in 1913 by A. T. B. Jacobson in determining that carbohydrate ingestion results in blood glucose fluctuations, [5] and the premise (named the Staub-Traugott Phenomenon after its first observers H. Staub in 1921 and K. Traugott in 1922) that a normal patient fed glucose will ...
However, some insulin analogues, such as insulin detemir, bind to albumin rather than fat like earlier insulin varieties, and results from long-term usage (e.g. more than 10 years) are currently not available but required for assessment of clinical benefit. Unmodified human and porcine insulins tend to complex with zinc in the blood, forming ...