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The concept of the sentinel lymph node is important because of the advent of the sentinel lymph node biopsy technique, also known as a sentinel node procedure. This technique is used in the staging of certain types of cancer to see if they have spread to any lymph nodes, since lymph node metastasis is one of the most important prognostic signs .
The sentinel node market experienced high growth in the early and mid-1990s, starting with melanoma sentinel node surgical search and breast cancer sentinel node staging; both are currently considered standards of care. [4] The use of a radioactive tracer, rather than a coloured dye, was proposed in 1984. [5] [6]
The general location of the sentinel node is determined with the use of a handheld scanner with a gamma-sensor probe that detects the technetium-99m–labeled tracer that was previously injected around the biopsy site. An injection of Methylene blue or isosulfan blue is done at the same time to dye any draining nodes visibly blue. An incision ...
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In surgeries such as sentinel lymph node dissections, methylene blue can be used to visually trace the lymphatic drainage of tested tissues. Similarly, methylene blue is added to bone cement in orthopedic operations to provide easy discrimination between native bone and cement.
The list starts out with a single node, the sentinel node which has the next and previous pointers point to itself. This condition determines if the list is empty. In a non-empty list, the sentinel node's next pointer gives the head of the list, and the previous pointer gives the tail of the list.
C cell – c-erbB-2 – c-kit – CA 19-9 assay – CA-125 – CA-125 test – cachexia – calcitonin – calcitriol – CAM – Campath-1H – camptothecin – camptothecin analog – cancer – cancer induction – Cancer Information Service – cancer of unknown primary origin – cancer stem cell – cancer vaccine – Cancer.gov – Candidiasis – Candidosis – CAP-1 – capecitabine ...
On the Varèse CD reissue, "Country Boy" is not the original "full band" version from the LP but rather an acoustic version with just Cash and his guitar, which is the demo version; however, the "full band" version is available on iTunes. "Country Boy" was re-recorded for his 1996 album Unchained during his American Recordings period.