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  2. Wolfram syndrome - Wikipedia

    en.wikipedia.org/wiki/Wolfram_syndrome

    Wolfram syndrome, also called DIDMOAD (diabetes insipidus, diabetes mellitus, optic atrophy, and deafness), is a rare autosomal-recessive genetic disorder that causes childhood-onset diabetes mellitus, optic atrophy, and deafness as well as various other possible disorders including neurodegeneration.

  3. ABO-incompatible transplantation - Wikipedia

    en.wikipedia.org/wiki/ABO-incompatible...

    This is known as ABO-incompatible (ABOi) transplantation. During the initial study period of 1996–2001, allowing for ABOi heart transplantation reduced infant mortality from 58% to 7%. [4] Graft survival and patient mortality is approximately the same between ABOi and ABOc recipients.

  4. Diabetes insipidus - Wikipedia

    en.wikipedia.org/wiki/Diabetes_insipidus

    Nephrogenic DI may be treated by addressing the underlying cause or by the use of a thiazide, aspirin or ibuprofen. [1] The number of new cases of diabetes insipidus each year is 3 in 100,000. [4] Central DI usually starts between the ages of 10 and 20 and occurs in males and females equally. [2] Nephrogenic DI can begin at any age. [3]

  5. Nephrogenic diabetes insipidus - Wikipedia

    en.wikipedia.org/wiki/Nephrogenic_diabetes_insipidus

    Both cause excessive urination (hence the similarity in name), but whereas diabetes insipidus is a problem with the production of antidiuretic hormone (neurogenic diabetes insipidus) or the kidneys' response to antidiuretic hormone (nephrogenic diabetes insipidus), diabetes mellitus causes polyuria via osmotic diuresis, due to the high blood ...

  6. Heart transplantation - Wikipedia

    en.wikipedia.org/wiki/Heart_transplantation

    A beating heart awaiting transplant. American medical researcher Simon Flexner was one of the first people to mention the possibility of heart transplantation. In 1907, he wrote the paper "Tendencies in Pathology," in which he said that it would be possible one day by surgery to replace diseased human organs – including arteries, stomach, kidneys and heart.

  7. Central diabetes insipidus - Wikipedia

    en.wikipedia.org/wiki/Central_diabetes_insipidus

    Central diabetes insipidus, recently renamed arginine vasopressin deficiency (AVP-D), [1] is a form of diabetes insipidus that is due to a lack of vasopressin (ADH) production in the brain. Vasopressin acts to increase the volume of blood (intravascularly), and decrease the volume of urine produced.

  8. Genetic causes of type 2 diabetes - Wikipedia

    en.wikipedia.org/wiki/Genetic_causes_of_type_2...

    Various hereditary conditions may feature diabetes, for example myotonic dystrophy and Friedreich's ataxia. Wolfram's syndrome is an autosomal recessive neurodegenerative disorder that first becomes evident in childhood. It consists of diabetes insipidus, diabetes mellitus, optic atrophy, and deafness, hence the acronym DIDMOAD. [20]

  9. Primary polydipsia - Wikipedia

    en.wikipedia.org/wiki/Primary_polydipsia

    As a diagnosis of exclusion, a diagnosis of primary polydipsia may be the result of elimination of the possibility of diseases causing similar signs and symptoms, such as diabetes insipidus. [ 12 ] Diagnosis may be complicated by the fact that chronic and extreme compulsive drinking may impair the response of the kidneys to vasopressin , thus ...

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