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It may be inherited, or caused by genetic mosaicism, chimerism, disease, or injury. [2] It occurs in humans and certain breeds of domesticated animals. Heterochromia of the eye is called heterochromia iridum or heterochromia iridis. It can be complete, sectoral, or central. In complete heterochromia, one iris is a different color from the other.
Some rare forms are inherited from only one parent. There are other genetic mutations which are proven to be associated with albinism. All alterations, however, lead to changes in melanin production in the body. [10] [16] The chance of offspring with albinism resulting from the pairing of an organism with albinism and one without albinism is low.
Occasionally, heterochromia can be a sign of a serious medical condition. A common cause in females with heterochromia is X-inactivation, which can result in a number of heterochromatic traits, such as calico cats. Trauma and certain medications, such as some prostaglandin analogues, can also cause increased pigmentation in one eye. [88]
Type 1 is characterised by congenital sensorineural hearing loss, pigmentary deficiencies of the hair such as a white lock of hair in the front-centre of the head or premature greying, pigmentary deficiencies of the eyes such as different-coloured eyes (complete heterochromia iridum), multiple colours in an eye (sectoral heterochromia iridum) or brilliant blue eyes, patches of skin ...
This results in either the entire surface (if all pigment cells fail to develop) or patches of body surface (if only a subset are defective) having a lack of cells that can make pigment. Since all pigment cell-types differentiate from the same multipotent precursor cell-type, leucism can cause the reduction in all types of pigment.
Image credits: djentrify #14. My mother was born with an upside-down uterus. They told her it would be impossible to have a child. I was born with my umbilical chord wrapped three times around my ...
Genetic testing company Color is mostly known for its DNA tests for cancer, but its most recent test kit is all about the heart. Color's new kit can detect predispositions to various inherited ...
The mother is a carrier of the recessive hereditary disposition for Color blindness. The Y chromosome of the father cannot oppose this. The healthy allele on the X chromosome of the father can compensate for this in a daughter. She can see normally, but she becomes a conductor. The same pattern of inheritance applies to Haemophilia.