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The main olfactory bulb has a multi-layered cellular architecture. In order from surface to the center the layers are: Glomerular layer; External plexiform layer; Mitral cell layer; Internal plexiform layer; Granule cell layer; The olfactory bulb transmits smell information from the nose to the brain, and is thus necessary for a proper sense of ...
In the olfactory bulb, the ORNs synapse with termination in the glomeruli. [6] Each glomerulus receives input from olfactory receptor neurons expressing only one type of olfactory receptor. The glomerular activation patterns within the olfactory bulb are thought to represent the quality of the odor being detected.
It has been proposed that, in an olfactory environment typically composed of multiple odor components (e.g., odor of a dog entering a kitchen that contains a background coffee odor), feedback from the olfactory cortex to the olfactory bulb [26] suppresses the pre-existing odor background (e.g., coffee) via olfactory adaptation, [27] so that the ...
Mitral cells are a neuronal cell type in the mammalian olfactory bulb, distinguished by the position of their somata located in an orderly row in the mitral cell layer of the bulb. [4] They typically have a single primary dendrite, which they project into a single glomerulus in the glomerular layer, and a few lateral dendrites that project ...
The Lady and the Unicorn, a Flemish tapestry depicting the sense of smell, 1484–1500. Musée national du Moyen Âge, Paris.. Early scientific study of the sense of smell includes the extensive doctoral dissertation of Eleanor Gamble, published in 1898, which compared olfactory to other stimulus modalities, and implied that smell had a lower intensity discrimination.
The olfactory epithelium contains olfactory sensory neurons, whose axons innervate the olfactory bulb. In order for olfactory sensory neurons to function properly, they must express odorant receptors and the proper transduction proteins on non-motile cilia that extend from the dendritic knob in addition to projecting their axons to the ...
This allows the granule cells to regulate the processing of the sensory input in the olfactory bulb. [21] The olfactory bulb transmits smell information from the nose to the brain, and is thus necessary for a proper sense of smell. Granule cells in the olfactory bulb have also been found to be important in forming memories linked with scents. [22]
The axons of OSNs expressing the same odorant receptors converge onto the same glomerulus at the olfactory bulb, allowing for the organization of olfactory information. An olfactory receptor neuron (ORN), also called an olfactory sensory neuron (OSN), is a sensory neuron within the olfactory system .