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Finasteride has been found to be effective in the treatment of hirsutism (excessive facial and/or body hair growth) in women. In a study of 89 women with hyperandrogenism due to persistent adrenarche syndrome , finasteride produced a 93% reduction in facial hirsutism and a 73% reduction of bodily hirsutism after 2 years of treatment.
Finasteride is one of two 5-alpha reductase inhibitors, along with dutasteride. 5-alpha reductase is an enzyme that your body eventually converts into a hormone called dihydrotestosterone (DHT).
Dihydrotestosterone (DHT, 5α-dihydrotestosterone, 5α-DHT, androstanolone or stanolone) is an endogenous androgen sex steroid and hormone primarily involved in the growth and repair of the prostate and the penis, as well as the production of sebum and body hair composition.
Dutasteride (Avodart) was the second steroidal 5α-reductase approved after finasteride. It is a competitive inhibitor of all three 5α-reductase isoenzymes [4] and it inhibits types 1 and 2 better than finasteride, leading to it causing further reduction in DHT, with >90% recuded DHT levels following 1 year of oral administration. [1]
Finasteride Research. Like other medications, finasteride went through several large-scale clinical trials before it received approval from the FDA (the federal gov body that assures the safety ...
Finasteride works by inhibiting an enzyme called 5-alpha-reductase, which converts part of your body’s testosterone into dihydrotestosterone, or DHT — the primary culprit behind male pattern ...
Two azasteroids, finasteride and dutasteride, are used clinically as 5α-reductase inhibitors. [1] [2] [3] Finasteride and dutasteride, two azasteroid pharmaceutical drugs. The nitrogen atoms in each ring system are highlighted in red. Some of the 6-azasteroids may prove to be useful drugs, but have yet to reach the pharmaceutical market. [4] [5]
Male pattern baldness (androgenetic alopecia) is a common issue that can happen to men of all ages. It can cause diffuse hair loss across the entire scalp, a receding hairline, a bald patch, or a ...