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Paroxetine, sold under the brand name Paxil among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [7] used to treat major depressive disorder, obsessive–compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder (PTSD), generalized anxiety disorder, and premenstrual dysphoric disorder. [7]
Hypomania, [7] [unreliable medical source] [8] [9] [unreliable medical source] may occur in as many as 8% of patients being treated with paroxetine. May be more common in those with bipolar disorder. Asthenia; Weight gain or loss. Usually gain, paroxetine tends to produce more weight gain than other SSRIs. [6]: 58 Confusion; Emotional lability ...
Paroxetine (Paxil, Pexeva) Sertraline (Zoloft) ... It can be caused by certain drug interactions, as well as drinking alcohol while taking a medication like Lexapro.
The effect was first discovered accidentally in 1989, when a test of drug interactions with alcohol used grapefruit juice to hide the taste of the ethanol. [ 9 ] [ 10 ] A 2005 medical review advised patients to avoid all citrus juices until further research clarifies the risks. [ 11 ]
Online, people claim they get brain zaps after stopping use of drugs like Lexapro (escitalopram), Cymbalta (duloxetine), and Paxil (paroxetine), but they can happen when you stop taking any type ...
Another important interaction of certain SSRIs involves paroxetine, a potent inhibitor of CYP2D6, and tamoxifen, an agent used commonly in the treatment and prevention of breast cancer. Tamoxifen is a prodrug that is metabolised by the hepatic cytochrome P450 enzyme system, especially CYP2D6, to its active metabolites.
As Gen-Z drinks less, other age groups follow suit. The most recent National Survey on Drug Use and Health found less than two-thirds of Americans drank alcohol at least once in 2022. According to ...
Alcohol is another substance that often cross-tolerates with other drugs. Findings of cross-tolerance with nicotine in animal models suggest that it is also possible in humans, and may explain why the two drugs are often used together. [6] Numerous studies have also suggested the possibility of cross-tolerance between alcohol and cannabis. [7]
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