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  2. Bioorthogonal chemistry - Wikipedia

    en.wikipedia.org/wiki/Bioorthogonal_chemistry

    The Staudinger ligation is a reaction developed by the Bertozzi group in 2000 that is based on the classic Staudinger reaction of azides with triarylphosphines. [15] It launched the field of bioorthogonal chemistry as the first reaction with completely abiotic functional groups although it is no longer as widely used.

  3. Orthogonal ligand-protein pair - Wikipedia

    en.wikipedia.org/wiki/Orthogonal_ligand-protein_pair

    Orthogonal ligand-protein pairs (also known as re-engineered ligand-receptor interfaces or re-engineered enzyme-substrate interactions) are a protein-ligand binding pair made to be independent of the original binding pair. This is done by taking a mutant protein (naturally occurring or selectively engineered), which is activated by a different ...

  4. Orthogonality - Wikipedia

    en.wikipedia.org/wiki/Orthogonality

    The line segments AB and CD are orthogonal to each other. In mathematics, orthogonality is the generalization of the geometric notion of perpendicularity.Whereas perpendicular is typically followed by to when relating two lines to one another (e.g., "line A is perpendicular to line B"), [1] orthogonal is commonly used without to (e.g., "orthogonal lines A and B").

  5. Design of experiments - Wikipedia

    en.wikipedia.org/wiki/Design_of_experiments

    Example of orthogonal factorial design Orthogonality concerns the forms of comparison (contrasts) that can be legitimately and efficiently carried out. Contrasts can be represented by vectors and sets of orthogonal contrasts are uncorrelated and independently distributed if the data are normal.

  6. Glossary of biology - Wikipedia

    en.wikipedia.org/wiki/Glossary_of_biology

    This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living organisms.It is intended as introductory material for novices; for more specific and technical definitions from sub-disciplines and related fields, see Glossary of cell biology, Glossary of genetics, Glossary of evolutionary biology, Glossary of ecology ...

  7. Concurrent tandem catalysis - Wikipedia

    en.wikipedia.org/wiki/Concurrent_tandem_catalysis

    Orthogonal tandem catalysis is a "one-pot reaction in which sequential catalytic processes occur through two or more functionally distinct, and preferably non-interfering, catalytic cycles". [7] This technique has been deployed in tandem alkane-dehydrogenation-olefin-metathesis catalysis [ 8 ] [ 9 ]

  8. Wikipedia:Reference desk/Archives/Science/2008 October 13 ...

    en.wikipedia.org/wiki/Wikipedia:Reference_desk/...

    "Orthogonal translation" is noted in several places in my lecture slides but no definition is given. -- M1ss1ontomars2k4 ( talk ) 16:43, 14 October 2008 (UTC) [ reply ] Alright, so it's translation (biology) , and "orthogonal" meaning "completely different of or independent from each other".

  9. Orthogenesis - Wikipedia

    en.wikipedia.org/wiki/Orthogenesis

    Evolutionary progress as a tree of life. Ernst Haeckel, 1866 Lamarck's two-factor theory involves 1) a complexifying force that drives animal body plans towards higher levels (orthogenesis) creating a ladder of phyla, and 2) an adaptive force that causes animals with a given body plan to adapt to circumstances (use and disuse, inheritance of acquired characteristics), creating a diversity of ...