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1-Boc-4-AP (tert-butyl 4-(phenylamino)piperidine-1-carboxylate) is a compound used as an intermediate in the manufacture of fentanyl, as well as various related derivatives such as butyrylfentanyl, furanylfentanyl, benzylfentanyl and homofentanyl, among others.
tert-Butyl alcohol is the simplest tertiary alcohol, with a formula of (CH 3) 3 COH (sometimes represented as t-BuOH). Its isomers are 1-butanol, isobutanol, and butan-2-ol. tert-Butyl alcohol is a colorless solid, which melts near room temperature and has a camphor-like odor. It is miscible with water, ethanol and diethyl ether.
Firstly, 2,4-dimethyl-6-tert-butylphenol is reacted with formaldehyde and HCl (Blanc reaction) to generate a chloromethyl group in the less hindered meta position. This intermediate then reacts with cyanuric acid to give the desired product.
4-tert-Butylphenol is an organic compound with the formula (CH 3) 3 CC 6 H 4 OH. It is one of three isomeric tert-butyl phenols. It is a white solid with a distinct phenolic odor. It dissolves in basic water. [2]
It is manufactured from acetic acid and isobutylene. [1] An attempt at Fischer esterification would lead to elimination of tert-butyl alcohol to isobutylene. Butyl acetate has four isomers (or five, including stereoisomers): tert-butyl acetate, n-butyl acetate, isobutyl acetate, and sec-butyl acetate (two enantiomers).
Tris(3,5-di-tert-butyl-4-hydroxybenzyl) isocyanurate is a high molecular weight additive, with low volatility. It is well suited to stabilising polyolefins against degradation caused by long term heat aging. [1] It is an approved food contact material in the US. [2]