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In the presence of neurological symptoms, following daily treatment, injections up to weekly or biweekly are indicated for six months before initiating monthly IM injections. Once clinical improvement is confirmed, maintenance supplementation of B 12 will generally be needed for life.
Shown is 500 mcg B-12 (as 1/2 cc) drawn up in a 0.5-cc U-100 27 gauge x 1/2" insulin syringe, as prepared for subcutaneous injection. Pernicious anemia is usually easily treated by providing the necessary level of vitamin B 12 supplementation. [63] Pernicious anemia can be treated with intramuscular injections of vitamin B 12. [64]
Vitamin B 12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B 12. [5] Symptoms can vary from none to severe. [1] Mild deficiency may have few or absent symptoms. [1]
Cyanocobalamin is a form of vitamin B 12 used to treat and prevent vitamin B 12 deficiency except in the presence of cyanide toxicity. [7] [8] [2] The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer. [9] [5] It is used by mouth, by injection into a muscle, or as a ...
[39]: 973 Breast milk B 12 decreases over months of nursing in both well-nourished and vitamin-deficient mothers. [39]: 973–974 Exclusive or near-exclusive breastfeeding beyond six months is a strong indicator of low serum vitamin status in nursing infants. This is especially true when the vitamin status is poor during the pregnancy and if ...
Adenosylcobalamin (AdoCbl), also known as coenzyme B 12, cobamamide, and dibencozide, is one of the biologically active forms of vitamin B 12. [ 1 ] Schematic diagram of the propionate metabolic pathway.