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Large granular lymphocytic (LGL) leukemia is a chronic lymphoproliferative disorder that exhibits an unexplained, chronic (> 6 months) elevation in large granular lymphocytes (LGLs) in the peripheral blood. [1] It is divided in two main categories: T-cell LGL leukemia (T-LGLL) and natural-killer (NK)-cell LGL leukemia (NK-LGLL).
Thomas P. Loughran, Jr. is an American physician-scientist who specializes in cancer research and treatment. He became director of the University of Virginia Cancer Center, F. Palmer Weber-Smithfield Foods Professor of Oncology Research and Professor of Medicine at the University of Virginia on August 15, 2013. [1]
UVA Cancer Center operates the LGL Leukemia Registry, the only national database and specimen bank from patients of the disease. [24] It is a member of the Oncology Research Information Exchange Network (ORIEN), a group of 16 institutions, as well as the Cooperative Human Tissue Network and the Applied Proteogenomics Organizational Learning and ...
T-cell leukemia describes several different types of lymphoid leukemia which affect T cells. Types include: [1] Large granular lymphocytic leukemia; Adult T-cell leukemia/lymphoma; T-cell prolymphocytic leukemia; In practice, it can be hard to distinguish T-cell leukemia from T-cell lymphoma, and they are often grouped together.
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Lymphoid leukemias are a group of leukemias affecting circulating lymphocytes, a type of white blood cell.The lymphocytic leukemias are closely related to lymphomas of the lymphocytes, to the point that some of them are unitary disease entities that can be called by either name (for example, adult T-cell leukemia/lymphoma).
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