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The drug has a terminal half-life of 5 to 6 hours in adult men (18–60 years of age) and a terminal half-life of 8 hours or more in elderly men (more than 70 years of age). [5] It is eliminated as its metabolites 57% in the feces and 40% in the urine .
Prescription drug list prices in the United States continually are among the highest in the world. [1] [2] The high cost of prescription drugs became a major topic of discussion in the 21st century, leading up to the American health care reform debate of 2009, and received renewed attention in 2015.
As of June 2022, the company had a selection of over 100 generic drugs, [7] and by March 2023, over 350 drugs were available. [8] In December 2023, the company had over 2200 drugs available. The drugs are sold for a price equivalent to the company's cost plus 15% markup, a $5 pharmacy service fee, and a $5 shipping fee.
Researchers examined data collected from 2011 to 2016 on 1,500 medicines that accounted for the highest total spending for Medicare Part D drug plans in 2015. This included 29 brand-name ...
Novo Nordisk's and Eli Lilly's weight loss drugs can cost over $1,000 for a month's supply, while compounded versions typically cost a few hundred dollars. The FDA needs more support, Califf said.
In 2027, negotiated prices will go into effect for 15 more drugs, followed by another 15 drugs in 2028 and 20 more in each subsequent year should the program remain in place.
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