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Feathery degeneration - large cells with pale flocculant cytoplasm (left-bottom and right-top). H&E stain . In histo pathology , feathery degeneration , formally feathery degeneration of hepatocytes , is a form of liver parenchymal cell (i.e. hepatocyte ) death associated with cholestasis .
Histopathology of a ballooning hepatocyte.png, H&E stain. Ballooning degeneration centre-left and centre-right. H&E stain. A Councilman body can also be seen in the upper-right of the section. In histo pathology, ballooning degeneration, formally ballooning degeneration of hepatocytes, is a form of liver parenchymal cell (i.e. hepatocyte) death.
Symptoms: None, tiredness, pain in the upper right side of the abdomen [1] [2] Complications: Cirrhosis, liver cancer, esophageal varices [1] [3] Types: Non-alcoholic fatty liver disease (NAFLD), alcoholic liver disease [1] Causes: Alcohol, diabetes, obesity [3] [1] Diagnostic method: Based on the medical history supported by blood tests ...
The hepatocytes are on a regular reticulin scaffold and less or equal to three cell thick. The histologic diagnosis of hepatic adenomas can be aided by reticulin staining. In hepatic adenomas, the reticulin scaffold is preserved and hepatocytes do not form layers of four or more hepatocytes, as is seen in hepatocellular carcinoma.
Macrovesicular steatosis is the more common form of fatty degeneration and may be caused by oversupply of lipids due to obesity, obstructive sleep apnea (OSA), [8] insulin resistance, or alcoholism. Nutrient malnutrition may also cause the mobilisation of fat from adipocytes and create a local oversupply in the liver where lipid metabolism occurs.
Signs and symptoms depend largely upon the primary lesions giving rise to the condition. In addition to the heart or lung symptoms, there will be a sense of fullness and tenderness in the right hypochondriac region. Gastrointestinal catarrh is usually present, and vomiting of blood may occur. There is usually more or less jaundice.
Symptoms may present acutely after a large amount of alcoholic intake in a short time period, or after years of excess alcohol intake. Signs and symptoms of alcoholic hepatitis include jaundice (yellowing of the skin and eyes), ascites (fluid accumulation in the abdominal cavity ), fatigue and hepatic encephalopathy ( brain dysfunction due to ...
Autoimmune hepatitis, formerly known as lupoid hepatitis, plasma cell hepatitis, or autoimmune chronic active hepatitis, is a chronic, autoimmune disease of the liver that occurs when the body's immune system attacks liver cells, causing the liver to be inflamed.
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