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If cancer has spread beyond the uterus, radiation, chemotherapy, and hormonal therapy may be used. If detected in its early stages, survival rates for uterine sarcoma are 66% after 5 years. If cancer has spread beyond the uterus, the survival rate declines to approximately 13-34%. [1]
Uterine serous carcinoma is a malignant form of serous tumor that originates in the uterus. It is an uncommon form of endometrial cancer that typically arises in postmenopausal women. It is typically diagnosed on endometrial biopsy , prompted by post-menopausal bleeding .
Uterine cancer effects approximately 3.1% of females during their lifetime. [8] Uterine cancer resulted in 45,000 deaths worldwide in 1990, with this number increasing to 58,000 deaths in 2010. [21] North America and Northern Europe have the highest rates of uterine cancer.
As with endometrial carcinomas, the prognosis is influenced by the grade and type of the adenocarcinoma, being poorest with serous differentiation. MMMTs are highly malignant; a stage I tumor has an expected five-year survival rate of 50%, while the overall five-year survival rate is less than 20%. [1] Staging of uterine MMMTs is as follows: [3]
Endometrial cancer is sometimes called "uterine cancer", although it is distinct from other forms of cancer of the uterus such as cervical cancer, uterine sarcoma, and trophoblastic disease. [9] The most frequent type of endometrial cancer is endometrioid carcinoma, which accounts for more than 80% of cases. [3]
In the United States there has been an increase in the 5-year relative survival rate between people diagnosed with cancer in 1975-1977 (48.9%) and people diagnosed with cancer in 2007-2013 (69.2%); these figures coincide with a 20% decrease in cancer mortality from 1950 to 2014. [8]