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  2. Rosuvastatin - Wikipedia

    en.wikipedia.org/wiki/Rosuvastatin

    As with all statins, there is a concern of rhabdomyolysis, a severe undesired side effect. The U.S. Food and Drug Administration (FDA) has indicated that "it does not appear that the risk [of rhabdomyolysis] is greater with Crestor than with other marketed statins", but has mandated that a warning about this side-effect, as well as a kidney ...

  3. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    The most important adverse side effects are muscle problems, an increased risk of diabetes mellitus, and increased liver enzymes in the blood due to liver damage. [ 5 ] [ 65 ] Over 5 years of treatment statins result in 75 cases of diabetes, 7.5 cases of bleeding stroke , and 5 cases of muscle damage per 10,000 people treated. [ 34 ]

  4. Methylnaltrexone - Wikipedia

    en.wikipedia.org/wiki/Methylnaltrexone

    Methylnaltrexone (MNTX, brand name Relistor), used in form of methylnaltrexone bromide (INN, USAN, BAN), is a medication that acts as a peripherally acting μ-opioid receptor antagonist that acts to reverse some of the side effects of opioid drugs such as constipation without significantly affecting pain relief or precipitating withdrawals.

  5. Crestor Backed by FDA for Patients With Normal ... - AOL

    www.aol.com/news/2009-12-16-crestor-backed-by...

    AstraZeneca (AZN) scored a win on Tuesday, when a Food and Drug Administration advisory panel recommended broader use of Crestor, the company's cholesterol-lowering drug. The panel recommended ...

  6. Dyslipidemia: What It Is & How to Treat It - AOL

    www.aol.com/dyslipidemia-treat-105700223.html

    Dyslipidemia is when the lipids in your blood are too high or too low. Estimates suggest that 53 percent of adults in the U.S. have lipid abnormalities.. Lipids are a type of fat that make up the ...

  7. Discovery and development of statins - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The difference in selectivity is because lipophilic statins passively and non-selectively diffuse into both hepatocyte and non-heptatocyte, while the hydrophilic statins rely largely on active transport into hepatocyte to exert their effects. [5] [12] High hepatoselectivity is thought to translate into reduced risk of adverse effects. [7]

  8. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    Cialis Drug Interactions. Tadalafil side effects aren’t the only concern when taking this drug. As mentioned, Cialis can interact with other PDE5 inhibitors for ED, as well as medications ...

  9. JUPITER trial - Wikipedia

    en.wikipedia.org/wiki/JUPITER_trial

    JUPITER was a randomized double-blind placebo-controlled study investigating the use of rosuvastatin in the primary prevention of cardiovascular disease.The trial focused on patients with normal low-density lipoprotein (LDL) cholesterol levels but increased levels of high-sensitivity C-reactive protein (hs-CRP).