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This is why all modern GWAS use a very low p-value threshold. In addition to easily correctible problems such as these, some more subtle but important issues have surfaced. A high-profile GWA study that investigated individuals with very long life spans to identify SNPs associated with longevity is an example of this. [72]
That is why GWAS use customizable arrays to genotype only a subset of the variants identified as tag snps. Most GWAS use products from the two primary genotyping platforms. The Affymetrix platform prints DNA probes on a glass or silicone chip that hybridize to specific alleles in the sample DNA.
In the field of genetic sequencing, genotyping by sequencing, also called GBS, is a method to discover single nucleotide polymorphisms (SNP) in order to perform genotyping studies, such as genome-wide association studies (). [1]
The geographic position of the Indian subcontinent makes its biodiversity important for the study of the early dispersal of anatomically modern humans across Asia. Based on mitochondrial DNA ( mtDNA ) variations, genetic unity across various South Asian subpopulations have shown that most of the ancestral nodes of the phylogenetic tree of all ...
The History of Pakistan prior to its independence in 1947 spans several millennia and covers a vast geographical area known as the Greater Indus region. [1] Anatomically modern humans arrived in what is now Pakistan between 73,000 and 55,000 years ago. [ 2 ]
Pakistan studies curriculum (Urdu: مطالعہ پاکستان Muṭāla-e-Pākistān) is the name [1] [2] of a curriculum of academic research and study that encompasses the culture, demographics, geography, history, International Relations and politics of Pakistan.
Gold medalist Arshad Nadeem of Team Pakistan celebrates after competing in the Men's Javelin Throw Final on day 13 of the Olympic Games at Stade de France on Aug. 8, 2024, in Paris Credit - Elsa ...
This is a timeline of Pakistani history, comprising important legal and territorial changes and political events in the region of modern-day Pakistan. To read about the background of these events, see History of Pakistan and History of the Islamic Republic of Pakistan .