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Shingles, also known as herpes zoster or zona, [6] is a viral disease characterized by a painful skin rash with blisters in a localized area. [2] [7] Typically the rash occurs in a single, wide mark either on the left or right side of the body or face. [1] Two to four days before the rash occurs there may be tingling or local pain in the area.
Brivudine is used for the treatment of herpes zoster in adult patients. It is taken orally once daily, in contrast to aciclovir, valaciclovir and other antivirals. [1] A study has found that it is more effective than aciclovir, but this has been disputed because of a possible conflict of interest on part of the study authors.
Shingles vaccination is the only way for adults to be protected against both shingles and postherpetic neuralgia, with the vaccine Shingrix providing 90% protection from postherpetic neuralgia. [3] The chickenpox vaccine is approved for infants to prevent chickenpox , which also protects against PHN from a herpes zoster infection.
Aciclovir topical cream is commonly associated (≥1% of patients) with dry or flaking skin or transient stinging/burning sensations. Infrequent adverse effects include erythema or itch. [15] When applied to the eye, aciclovir is commonly associated (≥1% of patients) with transient mild stinging.
Common side effects when applied as a cream include rash, redness, and burning. [4] Side effects of the injectable form include bone marrow suppression, vomiting, and seizures. [5] It is unclear if it is safe to use during pregnancy or breastfeeding. [5] It is recommended typically for children over the age of 12. [5]
Some common side effects include burning and stinging sensations. [10] [11] [21] [25] Colour change of the skin, bump formation on the skin and additional hair growth could also occur. [11] [19] Consult a doctor if these side effects persist or become worse. [11] [19] Some severe side effects are severe rash, swelling of the skin, and skin ...
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