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  2. Gabapentinoid - Wikipedia

    en.wikipedia.org/wiki/Gabapentinoid

    [6] [12] Existing evidence on the use of gabapentinoids in chronic lower back pain is limited, and demonstrates significant risk of adverse effects, without any demonstrated benefit. [13] The main side-effects include: a feeling of sleepiness and tiredness, decreased blood pressure, nausea, vomiting and also glaucomatous visual hallucinations. [14]

  3. Gabapentin - Wikipedia

    en.wikipedia.org/wiki/Gabapentin

    In recent years, gabapentin has seen increased use, particularly in the elderly. [25] There is concern regarding gabapentin's off-label use due to the lack of strong scientific evidence for its efficacy in multiple conditions, its proven side effects and its potential for misuse and physical/psychological dependency. [26] [27] [28]

  4. Gabapentin enacarbil - Wikipedia

    en.wikipedia.org/wiki/Gabapentin_enacarbil

    Gabapentin enacarbil (Horizant (ER) (U.S. Tooltip United States), Regnite (in Japan)) is an anticonvulsant and analgesic drug of the gabapentinoid class, and a prodrug to gabapentin. [1] It was designed for increased oral bioavailability over gabapentin, [ 2 ] [ 3 ] and human trials showed it to produce extended release of gabapentin with ...

  5. Mirogabalin - Wikipedia

    en.wikipedia.org/wiki/Mirogabalin

    Mirogabalin (brand name Tarlige; developmental code name DS-5565) is a gabapentinoid medication developed by Daiichi Sankyo. Gabapentin and pregabalin are also members of this class. As a gabapentinoid, mirogabalin binds to the α 2 δ subunit of voltage-gated calcium channel ( 1 and 2 ), but with significantly higher potency than pregabalin.

  6. Gabapentinoids - Wikipedia

    en.wikipedia.org/?title=Gabapentinoids&redirect=no

    On this Wikipedia the language links are at the top of the page across from the article title. Go to top.

  7. Vigabatrin - Wikipedia

    en.wikipedia.org/wiki/Vigabatrin

    Vigabatrin reduced cholecystokinin tetrapeptide-induced symptoms of panic disorder, in addition to elevated cortisol and ACTH levels, in healthy volunteers. [12]Vigabatrin is also used to treat seizures in succinic semialdehyde dehydrogenase deficiency (SSADHD), which is an inborn GABA metabolism defect that causes intellectual disability, hypotonia, seizures, speech disturbance, and ataxia ...

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