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In imaging of infections, the gallium scan has a sensitivity advantage over the indium white blood cell scan in imaging osteomyelitis (bone infection [3]) of the spine, lung infections and inflammation, and in detecting chronic infections. In part, this is because gallium binds to neutrophil membranes, even after neutrophil death, whereas ...
Chronic recurrent multifocal osteomyelitis (CRMO) is a rare condition (1:1,000,000), in which the bones have lesions, inflammation, and pain. It is called multifocal because it can appear in different parts of the body, primarily bones, and osteomyelitis because it is very similar to that disease, although CRMO appears to be without any infection .
More serious and life-threatening disorders as bone malignancies e.g. Ewing sarcoma and osteosarcoma may mimic septic arthritis associated with concurrent acute hematogenous osteomyelitis. In this regard, Magnetic resonance imaging may play an important role in the differential diagnosis. [5] [24]
A Brodie abscess is a subacute osteomyelitis, appearing as an accumulation of pus in bone, frequently with an insidious onset. [1] Brodie's abscess is characterized by pain and swelling without fever, often resulting from diabetic wounds, fracture-related bone infection, or haematogenous osteomyelitis.
In osteomyelitis involving the vertebral bodies, about half the cases are due to S. aureus, and the other half are due to tuberculosis (spread hematogenously from the lungs). Tubercular osteomyelitis of the spine was so common before the initiation of effective antitubercular therapy, it acquired a special name, Pott's disease. [citation needed]
Vertebral osteomyelitis is a type of osteomyelitis (infection and inflammation of the bone and bone marrow) that affects the vertebrae. It is a rare bone infection concentrated in the vertebral column. [2] Cases of vertebral osteomyelitis are so rare that they constitute only 2%-4% of all bone infections. [3]
Positron emission tomography–magnetic resonance imaging (PET–MRI) is a hybrid imaging technology that incorporates magnetic resonance imaging (MRI) soft tissue morphological imaging and positron emission tomography (PET) functional imaging. [1] The combination of PET and MRI was mentioned in a 1991 Phd thesis by R. Raylman. [2]
At the same time, CT imaging technology progressed rapidly and Genant and Boyd worked with one of EMI's first whole body CT systems in the late 1970s and early 1980s to apply the quantitative CT method to the spine, coining the term "QCT." Genant later published several articles on spinal QCT in the early 1980s with Christopher E. Cann, PhD.