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  2. Drug interaction - Wikipedia

    en.wikipedia.org/wiki/Drug_interaction

    When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. [2] Drug interactions can be of three kinds:

  3. Polypharmacy - Wikipedia

    en.wikipedia.org/wiki/Polypharmacy

    Every medication has potential adverse side-effects. With every drug added, there is an additive risk of side-effects. Also, some medications have interactions with other substances, including foods, other medications, and herbal supplements. [46] 15% of older adults are potentially at risk for a major drug-drug interaction. [47]

  4. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    NSAIDs, like all medications, may interact with other medications. For example, concurrent use of NSAIDs and quinolone antibiotics may increase the risk of quinolones' adverse central nervous system effects, including seizure. [47] [48] There is an argument over the benefits and risks of NSAIDs for treating chronic musculoskeletal pain.

  5. Grapefruit can interfere with your medications — here's what ...

    www.aol.com/grapefruit-interfere-medications...

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  6. List of herbs with known adverse effects - Wikipedia

    en.wikipedia.org/wiki/List_of_herbs_with_known...

    This is a partial list of herbs and herbal treatments with known or suspected adverse effects, either alone or in interaction with other herbs or drugs. Non-inclusion of an herb in this list does not imply that it is free of adverse effects.

  7. Additive effect - Wikipedia

    en.wikipedia.org/wiki/Additive_effect

    The antacids have no interaction between them, so they would be considered to have additive effect when taken together. Drugs that are in the same class, but do not have the same target, may also act additively by interacting with different targets in the same pathway. For example, propofol and sevoflurane can both produce anesthetic effects. [6]

  8. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    [19] [31] For drugs recently sold on the market, drugs have information pages (monographs) that provide information on any potential interaction between a medication and grapefruit juice. [19] Because there is a growing number of medications that are known to interact with citrus, [ 1 ] patients should consult a pharmacist or physician before ...

  9. Benzodiazepine - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine

    The largest group consists of those that are metabolized by cytochrome P450 (CYP450) enzymes and possess significant potential for interactions with other drugs. The other group comprises those that are metabolized through glucuronidation , such as lorazepam , oxazepam , and temazepam , and, in general, have few drug interactions.