Ad
related to: estrogen and tryptophan hydroxylase levels in blood test indicate kidney disease
Search results
Results From The WOW.Com Content Network
Risk factors for kidney disease include diabetes, high blood pressure, family history, older age, ethnic group and smoking. For most patients, a GFR over 60 (mL/min)/(1.73 m 2) is adequate. But significant decline of the GFR from a previous test result can be an early indicator of kidney disease requiring medical intervention.
Hypertryptophanemia is a rare autosomal recessive [2] metabolic disorder that results in a massive buildup of the amino acid tryptophan in the blood, with associated symptoms and tryptophanuria (-uria denotes 'in the urine'). [3] [4] Elevated levels of tryptophan are also seen in Hartnup disease, [5] a disorder of amino acid transport. [6]
In theory, 16α-OHE 1 could also bind DNA, although this has not been observed. 16α-OHE 2 is a potent ER agonist, capable of levels of cellular proliferation stimulation that near those obtained with E 2. [12] Though studies in hamster kidney tumor models showed weak carcinogenicity, the carcinogenic potential of 16α-OHE 2 in humans remains ...
Tryptophan hydroxylase (TPH; EC 1.14.16.4) is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility.[supplied by OMIM] [7]
Metabolites involved in the kynurenine pathway include tryptophan, kynurenine, kynurenic acid, xanthurenic acid, quinolinic acid, and 3-hydroxykynurenine. [2] [3] The kynurenine pathway is responsible for about 95% of total tryptophan catabolism. [4] Disruption in the pathway is associated with certain genetic and psychiatric disorders. [5] [2 ...
Tryptophan hydroxylase (TPH) is an enzyme (EC 1.14.16.4) involved in the synthesis of the monoamine neurotransmitter serotonin. Tyrosine hydroxylase , phenylalanine hydroxylase , and tryptophan hydroxylase together constitute the family of biopterin-dependent aromatic amino acid hydroxylases .
A study has revealed that serum progesterone concentrations in boys (10 days to 18 years old) with 21-hydroxylase deficiency reached levels up to 10.14 ng/mL, i.e. similar to female luteal values, while in the control group of boys average level was 0.07 ng/mL (0.22 nmol/L), with values ranging from 0.05 to 0.40 ng/mL. [38]
Children with blue diaper syndrome are put on restricted diets. This is in effort to reduce kidney damage. Restrictions include: calcium, protein, vitamin D, and tryptophan. Calcium is restricted to help prevent kidney damage. [3] Examples of food with high levels of tryptophan include turkey and milk. [3]