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Acute megakaryoblastic leukemia (AMKL) is life-threatening leukemia in which malignant megakaryoblasts proliferate abnormally and injure various tissues. Megakaryoblasts are the most immature precursor cells in a platelet-forming lineage; they mature to promegakaryocytes and, ultimately, megakaryocytes which cells shed membrane-enclosed particles, i.e. platelets, into the circulation.
Increased amounts of megakaryoblasts in the bone marrow may indicate a disease state. [4] An example of this is acute megakaryoblastic leukemia , which occurs when the level of megakaryoblasts in the bone marrow exceeds 20%.
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...
Heilmeyer-Schöner disease: Acute megakaryoblastic leukemia: D007947 Acute megakaryoblastic leukemia (AMKL) is a form of acute myeloid leukemia where megakaryoblasts account for approximately 30% of the nucleated cells within the bone marrow. [81] Mast cell leukemia: Panmyelosis: C94.4: Acute panmyelosis with myelofibrosis: C94.4
Doss porphyria/ALA dehydratase deficiency/Plumboporphyria (the disease is known by multiple names) ALD Alcoholic liver disease: ALI Acute lung injury: ALL Acute lymphoblastic lymphoma, acute lymphocytic leukemia: ALS Amyotrophic lateral sclerosis: AMD Age-related macular degeneration: AML Acute myelogenous leukemia: AN Anorexia nervosa: AOCD
Acute myeloid leukemia. Acute myeloid leukemia, secondary; Acute myelomonocytic leukemia; Acute necrotizing ulcerative gingivitis; Acute non lymphoblastic leukemia (generic term) Acute pancreatitis; Acute posterior multifocal placoid pigment epitheliopathy; Acute promyelocytic leukemia
The more aggressive forms of disease require treatment with chemotherapy, radiotherapy, immunotherapy and—in some cases—a bone marrow transplant. The use of rituximab has been established for the treatment of B-cell–derived hematologic malignancies, including follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL).
In medicine, describing a disease as acute denotes that it is of recent onset; it occasionally denotes a short duration.The quantification of how much time constitutes "short" and "recent" varies by disease and by context, but the core denotation of "acute" is always qualitatively in contrast with "chronic", which denotes long-lasting disease (for example, in acute leukaemia and chronic ...