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The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]
Management of depression is the treatment of depression that may involve a number of different therapies: medications, behavior therapy, psychotherapy, and medical devices. Depression is a symptom of some physical diseases; a side effect of some drugs and medical treatments; and a symptom of some mood disorders such as major depressive disorder ...
[15] [16] A family history of depression increases the chance of being diagnosed. [17] There are usually a combination of biological, psychological, and social factors that play into a person's depression. [2] [18] A major depressive episode can often follow acute stress in someone's life, such as the death of a loved one or being fired from a ...
Major depression is often associated with biomarkers indicative of inflammatory responses, with interleukin-6, interleukin-1, interleukin-2 receptor, tumor necrosis factor alpha, C-reactive protein, and monocyte chemotactic protein-1 all being found to be elevated in those with depression. [2] [8] [1] [5] [3] Similarly, the same biomarkers are ...
Major depressive disorder affected approximately 163 million people in 2017 (2% of the global population). [8] The percentage of people who are affected at one point in their life varies from 7% in Japan to 21% in France. In most countries the number of people who have depression during their lives falls within an 8–18% range.
Family history, previous diagnosis of a mood disorder, trauma, stress or major life changes in the case of depression, physical illness or use of certain medications. Depression has been linked to major diseases such as cancer, diabetes, Parkinson's disease and heart disease, Brain structure and function in the case of bipolar disorder. [1 ...
Mental health encompasses emotional, psychological, and social well-being, influencing cognition, perception, and behavior.According to the World Health Organization (WHO), it is a "state of well-being in which the individual realizes his or her abilities, can cope with the normal stresses of life, can work productively and fruitfully, and can contribute to his or her community". [1]
In physiology and medicine, depression [1] refers to a lowering, in particular a reduction in a specific biological variable or the functions of an organ. It is the opposite of elevation. For example, it is possible to refer to "depressed thyroid function" or to a depression of blood flow in a particular area. Further examples: