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Atypical depression is a chronic syndrome that tends to begin earlier in life than other forms of depression—usually beginning in the teenage years. Similarly, patients with atypical depression are more likely to have anxiety disorders, (such as generalized anxiety disorder, obsessive–compulsive disorder, and social anxiety disorder ...
A 2016 meta-analysis of transcranial direct current stimulation (tDCS) reported some efficacy of tDCS in the treatment of acute depressive disorder with moderate effect size, and low efficacy in treatment-resistant depression, and that use of 2 mA current strength over 20 minutes per day over a short time span can be considered safe. [166]
An atypical antidepressant is any antidepressant medication that acts in a manner that is different from that of most other antidepressants. Atypical antidepressants include agomelatine , bupropion , iprindole , mianserin , mirtazapine , nefazodone , opipramol , tianeptine , and trazodone .
The diagnosis of MD-NOS does not exist in the DSM-5, however the diagnoses of unspecified depressive disorder and unspecified bipolar disorder are in the DSM-5. [69] Most cases of MD-NOS represent hybrids between mood and anxiety disorders, such as mixed anxiety-depressive disorder or atypical depression. [68]
The treatment of a major depressive episode can be split into three phases: [27] Acute phase: the goal of this phase is to resolve the current major depressive episode. Continuation: this phase continues the same treatment from the acute phase for 4–8 months after the depressive episode has resolved, and the goal is to prevent relapse.
The Montgomery–Åsberg Depression Rating Scale (MADRS) is a ten-item [1] diagnostic questionnaire which mental health professionals use to measure the severity of depressive episodes in patients with mood disorders.
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