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Sepsis is defined as SIRS in response to an infectious process. [48] Severe sepsis is defined as sepsis with sepsis-induced organ dysfunction or tissue hypoperfusion (manifesting as hypotension, elevated lactate, or decreased urine output). Severe sepsis is an infectious disease state associated with multiple organ dysfunction syndrome (MODS) [9]
Many patients die due to sepsis; survivors are left with permanent scarring and disfigurement. [6] [7] Noma neonatorum is a severe infection affecting very young or newborn children in impoverished environments. A gangrenous infection spreads across the oral, nasal, and/or anal areas, and is frequently fatal.
It is categorized into four subtypes, with the first two being the most common. Type 1 requires an infection with an anaerobe and a species in the Enterobacteriaceae family, while type 2 is characterized by infection with Streptococcus pyogenes, a Gram-positive cocci bacteria, and thus is also known as hemolytic streptococcal gangrene. [24] [25]
B. fragilis is a Gram-negative bacterium and does not possess flagella or cilia making it immotile. However, it does utilize peritrichous fimbriae for adhesion to other molecular structures. B. fragilis also utilizes a complex series of surface proteins, lipopolysaccharide chains, and outer membrane vesicles to help survive the volatile ...
Infection usually begins in the mouth or nose and enters the central nervous system via the eyes. [ 5 ] If the fungal infection begins in the nose or sinus and extends to brain, symptoms and signs may include one-sided eye pain or headache , and may be accompanied by pain in the face, numbness, fever , loss of smell , a blocked nose or runny nose .
Boils – Boils are the most common type of staph infection, they are pockets of white pus that start where a hair follicle or oil gland is. The boil is tender and red where the infection is located on the skin. Impetigo – Impetigo is most prominent among children, and is usually located around their mouth, nose, hands, and feet. It shows up ...
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TCP was referred to numerous times in a running gag in Episode 2 of Series 2 of the BBC sitcom One Foot in the Grave, alluding to its distinctive and long-lasting odour. TCP was mentioned as an ingredient in a tonic in the film The Strange Case of the End of Civilization as We Know It (1977).