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  2. Clark's rule - Wikipedia

    en.wikipedia.org/wiki/Clark's_rule

    Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...

  3. WHO Model List of Essential Medicines for Children - Wikipedia

    en.wikipedia.org/wiki/WHO_Model_List_of...

    The selection and use of essential medicines: report of the WHO Expert Committee, 2017 (including the 20th WHO Model List of Essential Medicines and the 6th Model List of Essential Medicines for Children). Geneva: World Health Organization. hdl: 10665/259481. ISBN 978-92-4-121015-7. ISSN 0512-3054. WHO technical report series; no. 1006.

  4. Infliximab - Wikipedia

    en.wikipedia.org/wiki/Infliximab

    Infliximab, a chimeric monoclonal antibody, sold under the brand name Remicade among others, is a medication used to treat a number of autoimmune diseases. This includes Crohn's disease , ulcerative colitis , rheumatoid arthritis , ankylosing spondylitis , psoriasis , psoriatic arthritis , and Behçet's disease . [ 23 ]

  5. WHO Model List of Essential Medicines - Wikipedia

    en.wikipedia.org/wiki/WHO_Model_List_of...

    The selection and use of essential medicines. Twentieth report of the WHO Expert Committee 2015 (including 19th WHO Model List of Essential Medicines and 5th WHO Model List of Essential Medicines for Children). Geneva: World Health Organization. 2015. hdl: 10665/189763. ISBN 978-92-4-069494-1. ISSN 0512-3054. WHO technical report series; no. 994.

  6. Childhood-onset systemic lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Childhood-onset_systemic...

    Children taking this drug may develop bone marrow suppression and an increased susceptibility to infections. [ 65 ] Cyclophosphamide is used at 500 mg per dose for 6 doses every 2 weeks over a one-month period or six 500 to 750 mg intravenous doses per square meter of body surface for 3 years to treat severe cSLE disease and as induction ...

  7. Immunosuppressive drug - Wikipedia

    en.wikipedia.org/wiki/Immunosuppressive_drug

    A TNF-α (tumor necrosis factor-alpha) binding protein is a monoclonal antibody or a circulating receptor such as infliximab (Remicade), etanercept (Enbrel), or adalimumab (Humira) that binds to TNF-α, preventing it from inducing the synthesis of IL-1 and IL-6 and the adhesion of lymphocyte-activating molecules.

  8. Multisystem inflammatory syndrome in children - Wikipedia

    en.wikipedia.org/wiki/Multisystem_inflammatory...

    A child's condition can deteriorate rapidly, even in the presence of reassuring laboratory findings. [21] Many children develop shock and heart failure. [7] Most require paediatric intensive care. [7] Supplemental oxygen is often needed, and mechanical ventilation is sometimes used. [7] Most children who receive expert multidisciplinary care ...

  9. Management of Crohn's disease - Wikipedia

    en.wikipedia.org/wiki/Management_of_Crohn's_disease

    Adalimumab, like infliximab, is an antibody that targets tumor necrosis factor. [18] It has been shown to reduce the signs and symptoms of, and is approved for treatment of, moderate to severe Crohn's disease in adults who have not responded well to conventional treatments and who have lost response to or are unable to tolerate infliximab. [19]

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