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A classic example of this effect is the interaction between β-lactams, which damage the bacteria cell membrane, and aminoglycosides, which inhibit protein synthesis. [1] The damage dealt to the cell wall by β-lactams allows more aminoglycoside molecules to be taken up into the cell than would otherwise be possible, enhancing cell damage. [ 1 ]
Microbial synergy is a phenomenon in which aerobic and anaerobic microbes support each other's growth and proliferation. In this process aerobes invade and destroy host tissues, reduce tissue oxygen concentration and redox potential, thus creating favorable conditions for anaerobic growth and proliferation.
The study of antibiosis and its role in antibiotics has led to the expansion of knowledge in the field of microbiology. Molecular processes such cell wall synthesis and recycling, for example, have become better understood through the study of how antibiotics affect beta-lactam development through the antibiosis relationship and interaction of the particular drugs with the bacteria subjected ...
Microorganisms, or microbes, span all three domains of life – bacteria, archaea, and many unicellular eukaryotes including some fungi and protists.Typically defined as unicellular life forms that can only be observed with a microscope, microorganisms were the first cellular life forms, and were critical for creating the conditions for the evolution of more complex multicellular forms.
In Christian theology, synergism is the belief that salvation involves a cooperation between divine grace and human freedom. [40] Eastern Orthodox theology, in particular, uses the term "synergy" to describe this relationship, drawing on biblical language: "in Paul's words, 'We are fellow-workers (synergoi) with God' (1 Corinthians iii, 9)". [41]
Specimens for antibiotic sensitivity testing are ideally collected before treatment is started. [1] A sample may be taken from the site of a suspected infection; such as a blood culture sample when bacteria are suspected to be present in the bloodstream (bacteraemia), a sputum sample in the case of a pneumonia, or a urine sample in the case of ...
For example, the anthrax pathogen Bacillus anthracis releases two siderophores, bacillibactin and petrobactin, to scavenge ferric ion from iron containing proteins. While bacillibactin has been shown to bind to the immune system protein siderocalin , [ 12 ] petrobactin is assumed to evade the immune system and has been shown to be important for ...
Gram stains yield results much more quickly than culturing, and are especially important when infection would make an important difference in the patient's treatment and prognosis; examples are cerebrospinal fluid for meningitis and synovial fluid for septic arthritis.