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Heart failure with preserved ejection fraction (HFpEF) is a form of heart failure in which the ejection fraction – the percentage of the volume of blood ejected from the left ventricle with each heartbeat divided by the volume of blood when the left ventricle is maximally filled – is normal, defined as greater than 50%; [1] this may be measured by echocardiography or cardiac catheterization.
[10] [11] [18] To investigate its use for heart failure in those with a preserved LVEF (HFpEF), Novartis funded the PARAGON-HF trial which was designed to investigate the use of sacubitril/valsartan in the treatment of HFpEF patients with a LVEF of 45% or more. Concluding in 2019, it failed to show significance for reducing hospitalisation ...
In 2018, the American Heart Association and American College of Cardiology issued new guidelines for clinicians on the management of cholesterol as a way to reduce risk for heart attack and stroke. Newly included in the guidelines is a recommendation to use coronary artery calcium score if healthcare providers are having difficulty deciding if ...
From 2019 to 2024, Naidu was Governor and President of The New York State Chapter of the American College of Cardiology, and President of The New York Cardiological Society. In 2021 he was named to the Top 100 Notable Leaders in NY Healthcare in Crain's New York Business for his work in the national cardiovascular response to COVID-19.
Cardiotonic agents are typically employed as short-term and non-routine therapies for heart failure patients. [71] They are specifically reserved for those with contractile dysfunction in the left ventricles (lower chambers of the heart), low cardiac output, and low blood pressure, placing them at risk of inadequate organ perfusion. [72]
The American College of Cardiology (ACC), based in Washington, D.C., is a nonprofit medical association established in 1949. It bestows credentials upon cardiovascular specialists who meet its qualifications. Education is a core component of the college, which is also active in the formulation of health policy and the support of cardiovascular ...
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