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The advent of the first low dead space syringe occurred with the creation of 1-ml syringes designed specifically for the administration of insulin. Then amongst the scare of HIV and rising concern of other communicable diseases to healthcare workers the creation of safety syringes occurred in 1988.
The Tubex Syringe cartridge was developed c. 1943 during World War II by the Wyeth company. It is a drug pre-filled glass cartridge syringe with an attached sterile needle, which is inserted in a reusable stainless steel holder (now plastic). The product was manufactured for immediate injection once the pre-filled cartridge was attached to the ...
The dilution of insulin is such that 1 mL of insulin fluid has 100 standard "units" of insulin. [6] A typical insulin vial may contain 10 mL, for 1000 units. Insulin syringes are made specifically for a patient to inject themselves, and have features to assist this purpose when compared to a syringe for use by a healthcare professional:
Vial of vaccine and syringe Examples of modern flat-bottomed plastic vials Sterile single-use vial of eye drops. A vial (also known as a phial or flacon) is a small glass or plastic vessel or bottle, often used to store medication in the form of liquids, powders, or capsules.
Dosage forms (also called unit doses) are pharmaceutical drug products presented in a specific form for use. They contain a mixture of active ingredients and inactive components (), configured in a particular way (such as a capsule shell) and apportioned into a specific dose.
Alexander Wood's main contribution was the all-glass syringe in 1851, which allowed the user to estimate dosage based on the levels of liquid observed through the glass. [12] Wood used hypodermic needles and syringes primarily for the application of localized, subcutaneous injection (localized anesthesia) and therefore was not as interested in ...