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There is no level of BNP that perfectly separates patients with and without heart failure. [14] In screening for congenital heart disease in pediatric patients, an NT-proBNP cut-off value of 91 pg/mL could differentiate an acyanotic heart disease (ACNHD) patient from a healthy patient with a sensitivity of 84% and specificity of 42%. [15]
Brain natriuretic peptide (BNP), also known as B-type natriuretic peptide, is a hormone secreted by cardiomyocytes in the heart ventricles in response to stretching caused by increased ventricular blood volume. [5] BNP is one of the three natriuretic peptides, in addition to atrial natriuretic peptide and C-type natriuretic peptide ( CNP). [6]
Natriuretic peptide-binding receptors and ligand selectivity. [1] A natriuretic peptide is a hormone molecule that plays a crucial role in the regulation of the cardiovascular system. These hormones were first discovered in the 1980s and were found to have very strong diuretic, natriuretic, and vasodilatory effects.
Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
4880 18159 Ensembl ENSG00000163273 ENSMUSG00000026241 UniProt P23582 Q61839 RefSeq (mRNA) NM_024409 NM_010933 RefSeq (protein) NP_077720 NP_035063 Location (UCSC) Chr 2: 231.92 – 231.93 Mb Chr 1: 86.59 – 86.6 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Natriuretic peptide precursor C, also known as NPPC, is a protein that in humans is encoded by the NPPC gene. The precursor ...
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[1] [5] [6] Treatment of TIC can involve treating the heart failure as well as the tachycardia or arrhythmia. [1] TIC has a good prognosis with treatment, with most people recovering some to all of their heart function. [1] The number of cases that occur is unclear. [5] TIC has been reported in all age groups. [6]
Atrial natriuretic peptide (ANP) or atrial natriuretic factor (ANF) is a natriuretic peptide hormone secreted from the cardiac atria that in humans is encoded by the NPPA gene. [5] Natriuretic peptides (ANP, BNP , and CNP ) are a family of hormone/paracrine factors that are structurally related. [ 6 ]