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Thuja plicata Donn ex D. Don (Western red cedar) – a tree belonging to the Cupressaceae family from which thujaplicins were first purified. Thujaplicins were discovered in the mid-1930s and purified from the heartwood of Thuja plicata Donn ex D. Don, commonly called as Western red cedar tree. [5]
Thuja plicata is a large evergreen coniferous tree in the family Cupressaceae, native to the Pacific Northwest of North America. Its common name is western redcedar in the U.S. [2] or western red cedar in the UK, [3] and it is also called pacific red cedar, giant arborvitae, western arborvitae, just cedar, giant cedar, or shinglewood. [4]
Hinokitiol has been found in the heartwood of the conifer trees of the Cupressaceae family, including Chamaecyparis obtusa (Hinoki cypress), Thuja plicata (Western red cedar), Thujopsis dolabrata var. hondai (Hinoki asunaro), Juniperus cedrus (Canary Islands juniper), Cedrus atlantica (Atlas cedar), Cupressus lusitanica (Mexican white cedar), Chamaecyparis lawsoniana (Port Orford cedar ...
[25] T. plicata is an important tree to the First Nations people of the Pacific Northwest and is sometimes called "Canoe Tree" because of its use as a material for Native American canoes. [citation needed] Oil of Thuja contains the terpene thujone which has been studied for its GABA receptor antagonizing effects, with potentially lethal ...
Micrograph of fatty liver, as may be seen due to long-term prednisone use. Trichrome stain.. Short-term side effects, as with all glucocorticoids, include high blood glucose levels (especially in patients with diabetes mellitus or on other medications that increase blood glucose, such as tacrolimus) and mineralocorticoid effects such as fluid retention. [24]
The Duncan Cedar, also known as the Duncan Memorial Cedar and the Nolan Creek Tree, is a large specimen of Western redcedar. The tree is located on the Olympic Peninsula in the U.S. state of Washington. [1] It is currently the largest known Western redcedar in the world, [2] (compare to the Cheewhat Giant on Canada's Vancouver Island. [3]
The ACGIH has recommended a 0.5 mg/m3 Threshold Limit Value for western red cedar based on its asthma effects. Certain species of hardwood—such as oak, mahogany, beech, walnut, birch, elm, and ash— have been reported to cause nasal cancer in woodworkers. This is particularly true when exposures are high. [3]
Common side effects with long-term use include bone loss, weakness, yeast infections, and easy bruising. [6] While short-term use in the later part of pregnancy is safe, long-term use or use in early pregnancy is occasionally associated with harm to the baby. [1] It is a glucocorticoid made from hydrocortisone . [10]