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Drug tolerance develops when a medication no longer works as well as it once did. It’s different from dependence or addiction. If it happens, your doctor can help.
Drug tolerance occurs when someone’s body or brain no longer responds to a prescription or recreational drug in the same way it once did. In many...
Tolerance is typically seen with drugs that are active on brain receptors and stimulate the reward pathway. These drugs include alcohol, morphine, barbiturates, lysergic acid diethylamide (LSD), and amphetamines. Tolerance does not necessarily develop uniformly for all actions of a drug.
Drug tolerance or drug insensitivity is a pharmacological concept describing subjects' reduced reaction to a drug following its repeated use. Increasing its dosage may re-amplify the drug's effects; however, this may accelerate tolerance, further reducing the drug's effects.
Drug tolerance interferes with a drug's ability to deliver the intended benefit or effect. However, it also poses several potential problems that can lead to serious results.
Tolerance is a person's diminished response to a drug, which occurs when the drug is used repeatedly and the body adapts to the continued presence of the drug. Resistance refers to the ability of microorganisms or cancer cells to withstand the effects of a drug usually effective against them.
6 min read. The words “addiction,” “tolerance,” and “physical dependence” are often used interchangeably when it comes to drug or alcohol use. But they don’t mean the same thing. The words...
Drug dependence is a condition in which an individual experiences withdrawal symptoms and/or exhibits compulsive drug-seeking behavior due to physiological and psychological adaptations to drug use. Dependence can be both physical and psychological, and it often develops alongside drug tolerance.
What Is Drug Tolerance? The National Institute on Drug Abuse (NIDA) briefly defines drug tolerance as, “a state in which an organism no longer responds to a drug.” 1 To expand upon that, drug tolerance develops when a person no longer responds to a drug in the same way they used to.
What Is Drug Tolerance? Drug tolerance has to do with how effective a particular dose of a particular drug is in a particular person. With some drugs, tolerance can build over time. Narcotics or opiates are particularly subject to the development of tolerance, which is one reason why doctors must be careful about prescribing them.