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Reliant Pharmaceuticals was a company purchased by GlaxoSmithKline in December 2007 for $1.65B. [1] Co-founded by Joseph J. Krivulka. It was known for six major products, including Lovaza (Omega-3), Axid (H2 blocker), Dynacirc CR (calcium channel blocker), Antara (fenofibrate), InnoPran XL (beta blocker), Lescol XL (Fluvastatin), and Rythmol SR (Class IC anti-arrhythmic).
E-EPA was the second fish oil drug to be approved, after omega−3-acid ethyl esters (GlaxoSmithKline's Lovaza which was approved in 2004 [27]) and sales were not as robust at Amarin had hoped. The labels for the two drugs were similar, but doctors prescribed Lovaza for people who had triglycerides lower than 500 mg/dL based on some clinical ...
Color worked with San Francisco’s CityTestSF program, [11] Alameda County Health Services [12] and federally qualified health centers in Alameda County, Marin County and others. [13] The company has also partnered with a wide variety of universities, employers and public health entities, including USC [ 14 ] and United Airlines .
[10] [11] [12] The generic companies appealed, and in September 2013, the Federal Circuit reversed, saying that because more than one year before Pronova's predecessor company applied for a patent, it had sent samples of the fish oil used in Lovaza to a researcher for testing. This event thus constituted "public use" that invalidated the patent ...
Omega-3-acid ethyl esters are used in addition to changes in diet to reduce triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia. [3] In the European Union and other major markets outside the US, omega-3-acid ethyl esters are indicated for hypertriglyceridemia by itself, or in combination with a statin for people with mixed dyslipidemia.
From or to a drug trade name: This is a redirect from (or to) the trade name of a drug to (or from) the international nonproprietary name (INN).
Omega−3-carboxylic acids are used in addition to changes in diet to reduce triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia. [6]Intake of large doses (2.0 to 4.0 g/day) of long-chain omega−3 fatty acids as prescription drugs or dietary supplements are generally required to achieve significant (> 15%) lowering of triglycerides, and at those doses the effects ...
Fish oil became one of the earliest dietary supplements, and by the end of the 19th century, was used as a treatment for many diseases, including such ailments as tuberculosis and hysteria. [ 18 ] [ 19 ] [ 20 ] The possible effects of fish oil and omega−3 fatty acids have since been studied in clinical depression, [ 21 ] [ 22 ] anxiety , [ 23 ...