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In molecular biology, protein aggregation is a phenomenon in which intrinsically-disordered or mis-folded proteins aggregate (i.e., accumulate and clump together) either intra- or extracellularly. [1] [2] Protein aggregates have been implicated in a wide variety of diseases known as amyloidoses, including ALS, Alzheimer's, Parkinson's and prion ...
Accretion is defined as the gradual collection of something over time. [1] In meteorology or atmospheric science it is the process of accumulation of frozen water as precipitation over time as it descends through the atmosphere, in particular when an ice crystal or snowflake hits a supercooled liquid droplet, which then freeze together, increasing the size of the water particle.
The accumulation of platelets to the site of a wound to form a platelet plug or a thrombus; Flocculation, a process where a solute comes out of solution in the form of floccules or flakes; Overdispersion or statistical aggregation, where the variance of a distribution is higher than which we expect. Aggregation pheromone
In general, amyloid polymerization (aggregation or non-covalent polymerization) is sequence-sensitive, that is mutations in the sequence can induce or prevent self-assembly. [ 61 ] [ 62 ] For example, humans produce amylin , an amyloidogenic peptide associated with type II diabetes, but in rats and mice prolines are substituted in critical ...
Since absolute aggregation rates are difficult to measure, one often refers to the dimensionless stability ratio W, defined as = where k fast is the aggregation rate coefficient in the fast regime, and k the coefficient at the conditions of interest. The stability ratio is close to unity in the fast regime, increases in the slow regime, and ...
In astrophysics, accretion is the accumulation of particles into a massive object by gravitationally attracting more matter, typically gaseous matter, into an accretion disk. [ 1 ] [ 2 ] Most astronomical objects , such as galaxies , stars , and planets , are formed by accretion processes.
Glacier ice accumulation, an element in the glacier mass balance formula; Metabolic trapping, a localization mechanism of the synthesized radiocompounds in human body; Tree accumulation, in computer science, the process of accumulating data placed in tree nodes according to their tree structure; Accumulation point, another name for a limit point
Schematic of sediment accumulation (aggradation) in a river channel. The sediment is brown. The river is flowing on bedrock in the upper image, but because sediment was deposited over time the riverbed has risen. This has caused the house to be buried in the lower image.