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Treatment with adapalene gel daily for 4 weeks, and then twice daily thereafter for a total of nine months led to a significant but modest reduction in the number AKs compared to placebo; it demonstrated the additional advantage of improving the appearance of photodamaged skin. [66] Topical tretinoin is ineffective as treatment for reducing the ...
Adapalene, sold under the brand name Differin among others, is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions. [6] Studies have found adapalene is as effective as other retinoids, while causing less irritation. [7]
Synthetic retinoids are utilized in cosmetic formulations, clinical dermatology, and the treatment of some forms of cancer. [1] Retinoids have many important functions throughout the body, including in vision, [2] regulation of skin proliferation and differentiation, growth of bone tissue, immune function, [3] and male fertility. [4]
It contains clindamycin, as the phosphate, a lincosamide antibacterial; adapalene, a synthetic retinoid; and benzoyl peroxide, an oxidizing agent. [2] It is applied to the skin . [ 2 ]
Tretinoin, also known as all-trans retinoic acid (ATRA), is a medication used for the treatment of acne and acute promyelocytic leukemia. [ 8 ] [ 9 ] [ 10 ] For acne, it is applied to the skin as a cream, gel or ointment. [ 10 ]
Hyperpigmentation can be caused by sun damage, inflammation, or other skin injuries, including those related to acne vulgaris. [1] [2] [3]: 854 People with darker skin tones are more prone to hyperpigmentation, especially with excess sun exposure. [4] Many forms of hyperpigmentation are caused by an excess production of melanin. [4]
“Dark hair creates a frame that highlights the skin, while blonde or ash tones can soften the contrast and make the skin appear lighter,” she said, looking at Beyoncé’s pictures.
[6] Tri-Luma is the only FDA-approved drug containing hydroquinone, [7] a prescription product approved for the short-term treatment of dark spots associated with moderate-to-severe melasma of the face. FA+HQ+RA is effective in patients of all races/ethnicities and Fitzpatrick skin types.